Natera (NTRA) had the highest return in June 2018 by a large-cap US stock, returning 60.2%.

ASSET	MONTH	% RETURN
Natera (NTRA)	June 2018	60.17%
Carvana (CVNA)	June 2018	43.99%
Sarepta Therapeutics (SRPT)	June 2018	39.71%
Zscaler (ZS)	June 2018	35.62%
Warner Bros Discovery (WBD)	June 2018	29.84%
TKO (TKO)	June 2018	25.9%
Darden Restaurants (DRI)	June 2018	21.26%
Campbell Soup Company Common Stock (CPB)	June 2018	20.33%
Tesla (TSLA)	June 2018	19.97%
Liberty Media Corporation Series C Liberty Formula One Common Stock (FWONK)	June 2018	17.28%
Kroger (KR)	June 2018	16.93%
RPM International (RPM)	June 2018	16.9%
GameStop (GME)	June 2018	16.89%
Liberty Media Corporation Series A Liberty Formula One Common Stock (FWONA)	June 2018	16.61%
NetApp (NTAP)	June 2018	15.35%
McCormick (MKC)	June 2018	14.63%
Regeneron Pharmaceuticals (REGN)	June 2018	14.49%
Enbridge (ENB)	June 2018	14.46%
Wix (WIX)	June 2018	14.37%
Ciena (CIEN)	June 2018	14.27%
Molina Healthcare (MOH)	June 2018	14%
Live Nation Entertainment (LYV)	June 2018	13.59%
Roku (ROKU)	June 2018	13.5%
Church & Dwight (CHD)	June 2018	12.87%
Dollar General (DG)	June 2018	12.69%

Large-cap stocks are treated as having a market cap of $10B+.