Faraday Future Intelligent Electric (FFIE) had the highest return between 2016 and 2020 by a US stock, returning 994,718.7%.

ASSET	YEARS	% RETURN
Faraday Future Intelligent Electric (FFIE)	2016-2020	994,718.65%
JJill (JILL)	2016-2020	614,300%
Immatics (IMTX)	2016-2020	215,700%
AquaBounty Technologies (AQB)	2016-2020	121,566.67%
Kaival Brands Innovations (KAVL)	2016-2020	71,566.6%
Alarum Technologies (ALAR)	2016-2020	41,787.91%
Metalla Royalty & Streaming (MTA)	2016-2020	40,084.57%
Freedom (FRHC)	2016-2020	34,106.67%
Avalon GloboCare (ALBT)	2016-2020	23,900%
HIVE Blockchain Technologies (HIVE)	2016-2020	11,712.5%
Gravity (GRVY)	2016-2020	11,126.09%
Quantum Computing (QUBT)	2016-2020	9,978.57%
ABOT (ABOT)	2016-2020	9,528.85%
Accolade (ACCD)	2016-2020	7,809.09%
eXp World (EXPI)	2016-2020	7,414.26%
Nuvve (NVVEW)	2016-2020	5,366.67%
Enphase Energy (ENPH)	2016-2020	5,015.74%
Xpel (XPEL)	2016-2020	4,810.48%
New Pacific Metals (NEWP)	2016-2020	4,407.14%
Shopify Inc Class A Subordinate Voting Shares (SHOP)	2016-2020	4,352.99%
Digital Turbine (APPS)	2016-2020	4,217.56%
Eastside Distilling (BLNE)	2016-2020	4,152.28%
Cronos (CRON)	2016-2020	4,080.72%
Semler Scientific (SMLR)	2016-2020	3,736.73%
Ryvyl (RVYL)	2016-2020	3,306.25%