Hirequest (HQI) has had the highest return between 2000 and 2024 by a US stock, returning 7,284,900%.

ASSET	YEARS	% RETURN
Hirequest (HQI)	2000-2024	7,284,900%
Epsilon Energy (EPSN)	2000-2024	5,819,900%
Tectonic Therapeutic (TECX)	2000-2024	3,413,233.33%
Flotek Industries (FTK)	2000-2024	3,309,900%
Natwest (NWG)	2000-2024	1,709,900%
Gorilla Technology (GRRR)	2000-2024	1,544,900%
Cadrenal Therapeutics, Inc Common Stock (CVKD)	2000-2024	1,096,566.67%
Bragg Gaming (BRAG)	2000-2024	589,900%
Clene (CLNN)	2000-2024	423,233.33%
Shuttle Pharmaceuticals (SHPH)	2000-2024	199,025%
AppTech Payments Corp Warrant (APCXW)	2000-2024	196,400%
Asset Entities Inc Class B Common Stock (ASST)	2000-2024	172,866.67%
NVIDIA (NVDA)	2000-2024	155,033.04%
Deckers Outdoor (DECK)	2000-2024	143,541.98%
Immatics (IMTX)	2000-2024	141,100%
Monster Beverage (MNST)	2000-2024	117,994.17%
Perspective Therapeutics (CATX)	2000-2024	109,566.67%
Axon Enterprise (AXON)	2000-2024	106,843.25%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2000-2024	104,237.5%
Companhia Energetica de Minas Gerais CEMIG Pref ADR (CIG)	2000-2024	89,400%
MGO Global Inc Common Stock (MGOL)	2000-2024	88,100%
Texas Pacific Land Trust (TPL)	2000-2024	87,836.85%
Netflix (NFLX)	2000-2024	79,815.25%
authID (AUID)	2000-2024	50,300%
Zhihu Inc ADR (ZH)	2000-2024	49,215.07%