Xcel Brands (XELB) had the highest return between 1999 and 2001 by a US stock, returning 10,000%.

ASSET	YEARS	% RETURN
Xcel Brands (XELB)	1999-2001	9,999.96%
Worksport (WKSP)	1999-2001	7,900%
Algorhythm (RIME)	1999-2001	4,294.67%
Tritium Dcfc (DCFC)	1999-2001	3,263.64%
Flotek Industries (FTK)	1999-2001	2,650%
Versus Systems Inc. (VS)	1999-2001	2,300%
OPTIMIZERx (OPRX)	1999-2001	1,600%
NVIDIA (NVDA)	1999-2001	1,175.06%
RadNet (RDNT)	1999-2001	1,154.55%
Laboratory Corporation of America (LH)	1999-2001	1,076.11%
Suzano Papel e Celulose SA ADR (SUZ)	1999-2001	1,056.14%
Myriad Genetics (MYGN)	1999-2001	952.78%
FTI Consulting (FCN)	1999-2001	890.21%
Biogen (BIIB)	1999-2001	778.78%
Tandy Leather Factory (TLF)	1999-2001	731.81%
Quest Diagnostics (DGX)	1999-2001	707.99%
FuelCell Energy (FCEL)	1999-2001	698.82%
Integra LifeSciences (IART)	1999-2001	680.43%
Qualcomm (QCOM)	1999-2001	670.43%
Neurocrine Biosciences (NBIX)	1999-2001	633%
Novavax (NVAX)	1999-2001	627.74%
Euronet Worldwide (EEFT)	1999-2001	558.18%
Caesars Entertainment (CZR)	1999-2001	556.41%
US Physicalrapy (USPH)	1999-2001	525.54%
Logitech International (LOGI)	1999-2001	501.68%