Celestica (CLS) had the highest return between 2021 and 2024 by a large-cap US stock, returning 1,032.5%.

ASSET	YEARS	% RETURN
Celestica (CLS)	2021-2024	1,032.52%
Permian Resources (PR)	2021-2024	941.35%
NVIDIA (NVDA)	2021-2024	927.3%
Super Micro Computer (SMCI)	2021-2024	858.49%
Grupo Financiero Galicia SA ADR (GGAL)	2021-2024	783.73%
YPF Sociedad Anonima (YPF)	2021-2024	780.12%
Fortress Transp & Infra Inv (FTAI)	2021-2024	749.93%
Comfort Systems USA (FIX)	2021-2024	720.24%
Vistra Energy (VST)	2021-2024	676.26%
Targa Resources (TRGP)	2021-2024	620.16%
MicroStrategy (MSTR)	2021-2024	595.65%
GameStop (GME)	2021-2024	559.79%
Antero Resources (AR)	2021-2024	529.26%
Sprouts Farmers Market LLC (SFM)	2021-2024	529.06%
Arista Networks (ANET)	2021-2024	508.23%
Vertiv (VRT)	2021-2024	507.35%
Constellation Energy (CEG)	2021-2024	505.45%
Broadcom (AVGO)	2021-2024	481.3%
Credo Technology (CRDO)	2021-2024	455.45%
EMCOR (EME)	2021-2024	400.39%
Coca-Cola Consolidated (COKE)	2021-2024	390.7%
Texas Pacific Land Trust (TPL)	2021-2024	387.06%
Axon Enterprise (AXON)	2021-2024	383.15%
Reddit (RDDT)	2021-2024	380.71%
Eli Lilly and (LLY)	2021-2024	377.67%

Large-cap stocks are treated as having a market cap of $10B+.