Grupo Financiero Galicia SA ADR (GGAL) had the highest return in October 2015 by a large-cap US stock, returning 50.4%.

ASSET	MONTH	% RETURN
Grupo Financiero Galicia SA ADR (GGAL)	October 2015	50.37%
Trip Group Ltd ADR (TCOM)	October 2015	46.59%
Alibaba (BABA)	October 2015	40.89%
Trimble (TRMB)	October 2015	40.87%
YPF Sociedad Anonima (YPF)	October 2015	38.16%
New Oriental Education & Technology (EDU)	October 2015	35.58%
Baidu (BIDU)	October 2015	35.53%
KLA-Tencor (KLAC)	October 2015	34.29%
First Solar (FSLR)	October 2015	34.09%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	October 2015	32.56%
Las Vegas Sands (LVS)	October 2015	29.03%
Leidos (LDOS)	October 2015	28.31%
Autodesk (ADSK)	October 2015	26.35%
Wix (WIX)	October 2015	25.75%
PPG Industries (PPG)	October 2015	25.72%
MGM Resorts International (MGM)	October 2015	25.35%
Neurocrine Biosciences (NBIX)	October 2015	24.82%
United Rentals (URI)	October 2015	23.57%
Amazon (AMZN)	October 2015	22.49%
Southwest Airlines (LUV)	October 2015	22.4%
Monolithic Power Systems (MPWR)	October 2015	22.18%
Juniper Networks (JNPR)	October 2015	22.09%
SAP SE ADR (SAP)	October 2015	21.96%
Dupont De Nemours (DD)	October 2015	21.32%
Vertex Pharmaceuticals (VRTX)	October 2015	20.87%

Large-cap stocks are treated as having a market cap of $10B+.