Ferguson (FERG) had the highest return between 2006 and 2011 by a large-cap US stock, returning 14,392.8%.

ASSET	YEARS	% RETURN
Ferguson (FERG)	2006-2011	14,392.84%
Booking (BKNG)	2006-2011	1,995.48%
Baidu (BIDU)	2006-2011	1,712.76%
CF Industries (CF)	2006-2011	876.31%
Mastercard (MA)	2006-2011	840.61%
Ambev SA ADR (ABEV)	2006-2011	738.52%
Deckers Outdoor (DECK)	2006-2011	695.74%
Chipotle Mexican Grill (CMG)	2006-2011	650.53%
Credicorp (BAP)	2006-2011	462.1%
Apple (AAPL)	2006-2011	459.54%
Dollar Tree (DLTR)	2006-2011	420.03%
TechnipFMC (FTI)	2006-2011	407.09%
Wheaton Precious Metals (WPM)	2006-2011	386.86%
Transdigm (TDG)	2006-2011	372.23%
Somnigroup International (SGI)	2006-2011	371.03%
Monster Beverage (MNST)	2006-2011	357.61%
XPO Logistics (XPO)	2006-2011	347.43%
Novo Nordisk A-S (NVO)	2006-2011	347.2%
Clean Harbors (CLH)	2006-2011	343.49%
Illumina (ILMN)	2006-2011	327.79%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	2006-2011	323.04%
Cummins (CMI)	2006-2011	322.75%
Southern Copper (SCCO)	2006-2011	303.72%
Intuitive Surgical (ISRG)	2006-2011	289.44%
Coca-Cola Femsa SAB de CV ADR (KOF)	2006-2011	280.55%

Large-cap stocks are treated as having a market cap of $10B+.