NetEase (NTES) had the highest return between 2002 and 2007 by a large-cap US stock, returning 9,999.3%.

ASSET	YEARS	% RETURN
NetEase (NTES)	2002-2007	9,999.34%
Monster Beverage (MNST)	2002-2007	8,250.23%
Cheniere Energy (LNG)	2002-2007	6,772.31%
ArcelorMittal SA ADR (MT)	2002-2007	4,995.6%
Deckers Outdoor (DECK)	2002-2007	3,407.49%
Banco Bradesco SA ADR (BBD)	2002-2007	3,127.61%
Southern Copper (SCCO)	2002-2007	2,579.03%
Vale SA ADR (VALE)	2002-2007	2,471.91%
CME (CME)	2002-2007	1,724.81%
Apple (AAPL)	2002-2007	1,696.36%
Intuitive Surgical (ISRG)	2002-2007	1,547.87%
Tenaris SA ADR (TS)	2002-2007	1,465.73%
Clean Harbors (CLH)	2002-2007	1,443.28%
Hologic (HOLX)	2002-2007	1,376.13%
ICICI Bank (IBN)	2002-2007	1,364.32%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2002-2007	1,265.05%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2002-2007	1,215.62%
Canadian Natural Resources (CNQ)	2002-2007	1,187.29%
Axon Enterprise (AXON)	2002-2007	1,163.28%
First Solar (FSLR)	2002-2007	990.37%
Steel Dynamics (STLD)	2002-2007	971.01%
Credicorp (BAP)	2002-2007	955.04%
Cameco (CCJ)	2002-2007	933.44%
America Movil SAB de CV ADR (AMX)	2002-2007	931.28%
Crown (CCK)	2002-2007	905.9%

Large-cap stocks are treated as having a market cap of $10B+.