Azitra (AZTR) had the highest return between 2019 and 2023 by a US stock, returning 492,757.1%.

ASSET	YEARS	% RETURN
Azitra (AZTR)	2019-2023	492,757.14%
AppTech Payments Corp Warrant (APCXW)	2019-2023	350,000%
Applied Digital (APLD)	2019-2023	10,020.12%
Teekay Tankers (TNK)	2019-2023	5,393.92%
Celsius (CELH)	2019-2023	4,724.78%
Atlas Lithium Corporation Common Stock (ATLX)	2019-2023	4,534.07%
Centrus Energy (LEU)	2019-2023	3,217.68%
Graf Industrial Corp Warrants (each warrant exercisable for one-half of one share of common stock each at an exercise price of $1150 per share) (GRAF.WT)	2019-2023	3,121.34%
JIN MEDICAL INTERNATIONAL LTD Ordinary Shares (ZJYL)	2019-2023	3,000.63%
Oxbridge Re Holdings Equity Warrant (OXBRW)	2019-2023	2,990.91%
Enphase Energy (ENPH)	2019-2023	2,754%
374Water Inc Common Stock (SCWO)	2019-2023	2,740%
Axsome Therapeutics (AXSM)	2019-2023	2,732.38%
Cassava Sciences (SAVA)	2019-2023	2,548.24%
Accolade (ACCD)	2019-2023	2,083.64%
Super Micro Computer (SMCI)	2019-2023	1,961.35%
Sigma Lithium Resources (SGML)	2019-2023	1,931.57%
FitLife Brands, Inc Common Stock (FTLF)	2019-2023	1,810%
Aehr Test Systems (AEHR)	2019-2023	1,768.31%
Empire Petroleum (EP)	2019-2023	1,731.52%
ELF Beauty (ELF)	2019-2023	1,592.15%
Weatherford International (WFRD)	2019-2023	1,548.36%
Impact BioMedical (IBO)	2019-2023	1,542.53%
Golden Matrix (GMGI)	2019-2023	1,506.67%
Quipt Home Medical (QIPT)	2019-2023	1,490.63%