Graphex (GRFX) has had the highest return between 2021 and 2025 by a US stock, returning 198,233.3%.

ASSET	YEARS	% RETURN
Graphex (GRFX)	2021-2025	198,233.33%
AppTech Payments Corp Warrant (APCXW)	2021-2025	177,200%
Wearable Devices (WLDSW)	2021-2025	13,911.3%
Azitra (AZTR)	2021-2025	5,310.71%
Applied Digital (APLD)	2021-2025	2,397.78%
Kolibri Global Energy Inc Common stock (KGEI)	2021-2025	1,997.5%
Diginex Limited Ordinary Shares (DGNX)	2021-2025	1,982.16%
Zivo Bioscience (ZIVO)	2021-2025	1,775%
Vista Oil Gas ADR (VIST)	2021-2025	1,697.68%
Cresud SACIF y A Warrant (CRESW)	2021-2025	1,560%
Alpha Metallurgical Resources (AMR)	2021-2025	1,062.46%
TSS, Inc Common Stock (TSSI)	2021-2025	982.76%
Super Micro Computer (SMCI)	2021-2025	976.73%
Tecnoglass (TGLS)	2021-2025	970.31%
Natural Resource Partners (NRP)	2021-2025	930.97%
Permian Resources (PR)	2021-2025	914.13%
Build-A-Bear Workshop (BBW)	2021-2025	891.91%
ADMA Biologics (ADMA)	2021-2025	882.18%
Celestica (CLS)	2021-2025	866.99%
Energy Services Of America (ESOA)	2021-2025	865.47%
Cohen Circle Acquisition Corp I Warrant (CCIRW)	2021-2025	847.37%
Sezzle Inc Common Stock (SEZL)	2021-2025	824.24%
Weatherford International (WFRD)	2021-2025	810.39%
Nixxy (NIXXW)	2021-2025	804.76%
Verona Pharma PLC ADR (VRNA)	2021-2025	800.57%