Axsome Therapeutics (AXSM) had the highest return between 2019 and 2019 by a US stock, returning 3,578.3%.

ASSET	YEARS	% RETURN
Axsome Therapeutics (AXSM)	2019-2019	3,578.29%
FitLife Brands, Inc Common Stock (FTLF)	2019-2019	3,425%
Sobr Safe (SOBR)	2019-2019	3,309.09%
Teekay Tankers (TNK)	2019-2019	2,442.71%
Nocera (NCRA)	2019-2019	1,233.33%
Oxbridge Re Holdings Equity Warrant (OXBRW)	2019-2019	1,009.09%
Kodiak Sciences (KOD)	2019-2019	919.12%
Quipt Home Medical (QIPT)	2019-2019	833.75%
Splash Beverage (SBEV)	2019-2019	750%
Relmada Therapeutics (RLMD)	2019-2019	747.83%
EverQuote Inc Class A (EVER)	2019-2019	725.72%
Avita Medical (RCEL)	2019-2019	719.82%
Durect (DRRX)	2019-2019	691.67%
Iveda Solutions (IVDA)	2019-2019	669.23%
Castellum (CTM)	2019-2019	618.12%
Netcapital (NCPL)	2019-2019	600%
Nisun International Enterprise Development (NISN)	2019-2019	590.56%
Battalion Oil (BATL)	2019-2019	572.5%
Microbot Medical (MBOT)	2019-2019	516.36%
Cassava Sciences (SAVA)	2019-2019	511.76%
Orion Energy Systems (OESX)	2019-2019	498.21%
Cardlytics (CDLX)	2019-2019	491.9%
Neurogene (NGNE)	2019-2019	473.02%
Enphase Energy (ENPH)	2019-2019	464.36%
Pennant (PNTG)	2019-2019	437.72%