XTI Aerospace (XTIA) had the best year in the 2010s by a US stock in 2012, returning 243,902,339%.

ASSET	YEAR	% RETURN
XTI Aerospace (XTIA)	2012	243,902,339%
Clene (CLNN)	2018	16,499,900%
Alarum Technologies (ALAR)	2018	4,829,168.29%
Scienture (SCNX)	2012	4,004,714.29%
Enveric Biosciences (ENVB)	2015	3,407,230.92%
Avalon GloboCare (ALBT)	2018	2,578,025%
Scienture (SCNX)	2014	1,134,592.86%
Luokung Technology (LKCO)	2019	938,029.5%
Scinai Immunotherapeutics (SCNI)	2015	791,900%
Nutex Health (NUTX)	2013	749,900%
Skye Bioscience, Inc Common Stock (SKYE)	2015	564,416.13%
Salarius Pharmaceuticals (SLRX)	2015	388,962.5%
Proficient Auto Logistics, Inc Common Stock (PAL)	2015	332,290.38%
Immatics (IMTX)	2018	195,900%
Aris Mining (ARMN)	2010	184,106.18%
Versus Systems Inc. (VS)	2012	163,639.24%
CEA Industries (CEAD)	2014	156,830.69%
Enveric Biosciences (ENVB)	2012	154,627.11%
Nixxy (NIXX)	2012	64,900%
PetVivo (PETV)	2014	64,689.33%
Bragg Gaming (BRAG)	2018	33,268.98%
NextTrip (NTRP)	2010	19,900%
Ryvyl (RVYL)	2010	18,361.54%
XTI Aerospace (XTIA)	2011	14,328.57%
Clearpoint Neuro (CLPT)	2012	8,433.33%