Perspective Therapeutics (CATX) had the highest return between 2003 and 2012 by a US stock, returning 259,900%.

ASSET	YEARS	% RETURN
Perspective Therapeutics (CATX)	2003-2012	259,900%
VirnetX (VHC)	2003-2012	70,378.45%
Aris Mining (ARMN)	2003-2012	52,857.06%
Know Labs (KNW)	2003-2012	34,251.15%
Monster Beverage (MNST)	2003-2012	19,960.82%
Dawson Geophysical (DWSN)	2003-2012	17,801.51%
Universal Insurance (UVE)	2003-2012	16,563.16%
Pioneer Power Solutions (PPSI)	2003-2012	11,111.15%
BRF SA ADR (BRFS)	2003-2012	10,234.63%
DXP Enterprises (DXPE)	2003-2012	9,428.16%
Apple (AAPL)	2003-2012	7,381.45%
Companhia Energetica de Minas Gerais CEMIG Pref ADR (CIG)	2003-2012	6,767.55%
Booking (BKNG)	2003-2012	6,282.66%
Silicom (SILC)	2003-2012	5,879.29%
Gulf Resources (GURE)	2003-2012	5,700%
Banco Bradesco SA ADR (BBD)	2003-2012	5,508.05%
Millicom International Cellular (TIGO)	2003-2012	5,090.75%
NewMarket (NEU)	2003-2012	4,782.7%
WisdomTree (WT)	2003-2012	4,607.8%
Cocrystal Pharma (COCP)	2003-2012	4,233.33%
Bancolombia SA ADR (CIB)	2003-2012	4,017.79%
Intuitive Surgical (ISRG)	2003-2012	3,886.95%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	2003-2012	3,594.66%
Deckers Outdoor (DECK)	2003-2012	3,549.65%
Ambev SA ADR (ABEV)	2003-2012	3,416.11%