Tectonic Therapeutic (TECX) has had the highest return between 2008 and 2024 by a US stock, returning 3,206,566.7%.

ASSET	YEARS	% RETURN
Tectonic Therapeutic (TECX)	2008-2024	3,206,566.67%
A2Z Smart Technologies (AZ)	2008-2024	1,156,566.67%
Cadrenal Therapeutics, Inc Common Stock (CVKD)	2008-2024	999,233.33%
HIVE Blockchain Technologies (HIVE)	2008-2024	817,900%
Bragg Gaming (BRAG)	2008-2024	551,566.67%
Gorilla Technology (GRRR)	2008-2024	477,900%
MGO Global Inc Common Stock (MGOL)	2008-2024	469,900%
Clene (CLNN)	2008-2024	347,400%
Shuttle Pharmaceuticals (SHPH)	2008-2024	217,650%
Asset Entities Inc Class B Common Stock (ASST)	2008-2024	212,800%
AppTech Payments Corp Warrant (APCXW)	2008-2024	199,700%
Immatics (IMTX)	2008-2024	151,700%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2008-2024	131,150%
authID (AUID)	2008-2024	52,380%
Zhihu Inc ADR (ZH)	2008-2024	49,215.07%
Alarum Technologies (ALAR)	2008-2024	44,737.76%
Tesla (TSLA)	2008-2024	27,732.95%
Netflix (NFLX)	2008-2024	23,561.54%
NVIDIA (NVDA)	2008-2024	18,047.53%
Pioneer Power Solutions (PPSI)	2008-2024	17,900%
Broadcom (AVGO)	2008-2024	13,670.75%
Texas Pacific Land Trust (TPL)	2008-2024	13,492.83%
Skye Bioscience, Inc Common Stock (SKYE)	2008-2024	10,200%
Ainos (AIMD)	2008-2024	9,812.77%
XPO Logistics (XPO)	2008-2024	9,695.5%