NVIDIA (NVDA) has had the highest return between 2020 and 2025 by a US stock in the S&P 500 (GSPC), returning 2,413.8%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2020-2025	2,413.84%
Super Micro Computer (SMCI)	2020-2025	1,428.3%
Tesla (TSLA)	2020-2025	1,352.47%
Arista Networks (ANET)	2020-2025	825.55%
Broadcom (AVGO)	2020-2025	752.79%
Vistra Energy (VST)	2020-2025	709.53%
Quanta Services (PWR)	2020-2025	708.78%
Axon Enterprise (AXON)	2020-2025	671.02%
Palantir Technologies Inc Class A Common Stock (PLTR)	2020-2025	659.2%
Deckers Outdoor (DECK)	2020-2025	636.95%
Crowdstrike (CRWD)	2020-2025	632.28%
Constellation Energy (CEG)	2020-2025	615.25%
Eli Lilly and (LLY)	2020-2025	519.37%
Carrier Global (CARR)	2020-2025	510.38%
Builders FirstSource (BLDR)	2020-2025	469.17%
KKR (KKR)	2020-2025	441.5%
Fair Isaac (FICO)	2020-2025	422.02%
Texas Pacific Land Trust (TPL)	2020-2025	417.91%
Targa Resources (TRGP)	2020-2025	413.47%
Dell Technologies (DELL)	2020-2025	406.34%
Howmet Aerospace (HWM)	2020-2025	380.23%
Palo Alto Networks (PANW)	2020-2025	361.76%
EQT (EQT)	2020-2025	359.74%
Fortinet (FTNT)	2020-2025	355.11%
Cadence Design Systems (CDNS)	2020-2025	339.07%