Applied Digital (APLD) has had the highest return between 2020 and 2025 by a US stock in the Nasdaq Composite (IXIC), returning 22,562%.

ASSET	YEARS	% RETURN
Applied Digital (APLD)	2020-2025	22,562.04%
Ainos (AIMD)	2020-2025	20,375%
Innodata (INOD)	2020-2025	3,738.6%
CPI Card (PMTS)	2020-2025	3,413.33%
MicroStrategy (MSTR)	2020-2025	2,553.95%
Limbach (LMB)	2020-2025	2,530.11%
NVIDIA (NVDA)	2020-2025	2,413.84%
Marathon Digital (MARA)	2020-2025	2,203.41%
Indivior PLC Ordinary Shares (INDV)	2020-2025	2,022.34%
Celsius (CELH)	2020-2025	1,696.89%
Energy Services Of America (ESOA)	2020-2025	1,579%
Super Micro Computer (SMCI)	2020-2025	1,428.3%
Byrna Technologies (BYRN)	2020-2025	1,352.63%
Tesla (TSLA)	2020-2025	1,352.47%
Red Cat (RCAT)	2020-2025	1,190%
Sterling Construction (STRL)	2020-2025	1,149.3%
Weatherford International (WFRD)	2020-2025	1,145.28%
Fortress Transp & Infra Inv (FTAI)	2020-2025	1,130.97%
Sezzle Inc Common Stock (SEZL)	2020-2025	1,118.76%
Celldex Therapeutics (CLDX)	2020-2025	1,086.61%
Lifeway Foods (LWAY)	2020-2025	1,078.68%
Capricor Therapeutics (CAPR)	2020-2025	1,053.85%
Riot Blockchain (RIOT)	2020-2025	1,030.7%
Summit Therapeutics (SMMT)	2020-2025	991.88%
Euroseas (ESEA)	2020-2025	983.77%