VeriSign (VRSN) had the highest return between 1997 and 1999 by a US stock with a market cap of $2B+, returning 3,625.6%.

ASSET	YEARS	% RETURN
VeriSign (VRSN)	1997-1999	3,625.61%
Qualcomm (QCOM)	1997-1999	3,561.24%
Skyworks Solutions (SWKS)	1997-1999	3,175.18%
Amazon (AMZN)	1997-1999	3,022.48%
Viavi Solutions (VIAV)	1997-1999	2,346.46%
American Eagle Outfitters (AEO)	1997-1999	2,317.87%
Best Buy (BBY)	1997-1999	1,791.86%
Qorvo (QRVO)	1997-1999	1,666.15%
Nokia (NOK)	1997-1999	1,267.8%
MicroStrategy (MSTR)	1997-1999	1,192.31%
NetApp (NTAP)	1997-1999	1,190.25%
InterDigital (IDCC)	1997-1999	1,176.6%
Semtech (SMTC)	1997-1999	1,117.48%
Power Integrations (POWI)	1997-1999	1,027.96%
F5 Networks (FFIV)	1997-1999	1,012.2%
Cognizant Technology Solutions Corp Class A (CTSH)	1997-1999	993.37%
Sirius XM (SIRI)	1997-1999	888.89%
Advanced Energy Industries (AEIS)	1997-1999	838.09%
ASML Holding NV ADR (ASML)	1997-1999	819.2%
Check Point Software Technologies (CHKP)	1997-1999	819.07%
Infosys Ltd ADR (INFY)	1997-1999	783.34%
Biogen (BIIB)	1997-1999	727.38%
Jabil Circuit (JBL)	1997-1999	658.44%
Cisco Systems (CSCO)	1997-1999	657.67%
Dycom Industries (DY)	1997-1999	614.53%