Gorilla Technology (GRRR) had the highest return between 2016 and 2022 by a US stock, returning 8,109,900%.

ASSET	YEARS	% RETURN
Gorilla Technology (GRRR)	2016-2022	8,109,900%
ZyVersa Therapeutics (ZVSA)	2016-2022	1,955,416.01%
Shuttle Pharmaceuticals (SHPH)	2016-2022	1,742,122.22%
Clene (CLNN)	2016-2022	1,666,566.67%
A2Z Smart Technologies (AZ)	2016-2022	529,066.67%
XORTX Therapeutics (XRTX)	2016-2022	411,522.64%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2016-2022	277,775%
Crown Electrokinetics (CRKN)	2016-2022	188,900%
Immatics (IMTX)	2016-2022	174,100%
AppTech Payments Corp Warrant (APCXW)	2016-2022	140,200%
Zhihu Inc ADR (ZH)	2016-2022	106,749.32%
Luokung Technology (LKCO)	2016-2022	86,806.47%
Fresh2 (FRES)	2016-2022	83,026.11%
Bragg Gaming (BRAG)	2016-2022	41,297.85%
Freedom (FRHC)	2016-2022	38,713.33%
Immunoprecise Antibodies (IPA)	2016-2022	34,633.33%
Metalla Royalty & Streaming (MTA)	2016-2022	15,608.36%
Kaival Brands Innovations (KAVL)	2016-2022	12,372.22%
Avalon GloboCare (ALBT)	2016-2022	11,042.86%
Connexa Sports Technologies (YYAI)	2016-2022	9,260%
authID (AUID)	2016-2022	9,108.75%
Enphase Energy (ENPH)	2016-2022	7,624.78%
Alarum Technologies (ALAR)	2016-2022	6,979.65%
Xpel (XPEL)	2016-2022	5,620%
SilverCrest Metals (SILV)	2016-2022	5,266.73%