MDxHealth SA ADR (MDXH) has had the highest return between 2023 and 2025 by a US stock, returning 156,900%.

ASSET	YEARS	% RETURN
MDxHealth SA ADR (MDXH)	2023-2025	156,900%
Wearable Devices (WLDSW)	2023-2025	108,520.69%
Synergy CHC Corp Common Stock (SNYR)	2023-2025	6,304.29%
Azitra (AZTR)	2023-2025	6,137.5%
Rigetti Computing Inc Warrants (RGTIW)	2023-2025	5,525%
Carvana (CVNA)	2023-2025	3,777.34%
Root (ROOT)	2023-2025	3,378.08%
Bone Biologics Corp Warrants (BBLGW)	2023-2025	3,266.67%
Applovin (APP)	2023-2025	2,738.58%
Soleno Therapeutics (SLNO)	2023-2025	2,274.64%
MicroStrategy (MSTR)	2023-2025	1,920.11%
SoundHound AI (SOUNW)	2023-2025	1,706.02%
TSS, Inc Common Stock (TSSI)	2023-2025	1,683.06%
NewAmsterdam Pharma Company NV Warrant (NAMSW)	2023-2025	1,645.01%
Fold Holdings, Inc Warrant (FLDDW)	2023-2025	1,540%
Diginex Limited Ordinary Shares (DGNX)	2023-2025	1,421.13%
Regis Corporation Common Stock (RGS)	2023-2025	1,420.83%
Innodata (INOD)	2023-2025	1,391.23%
Rigetti Computing (RGTI)	2023-2025	1,388%
ADS-TEC ENERGY PLC Warrant (ADSEW)	2023-2025	1,288.03%
Goldenstone Acquisition Limited Warrants (GDSTW)	2023-2025	1,252.24%
Palantir Technologies Inc Class A Common Stock (PLTR)	2023-2025	1,227.51%
Helport AI Limited Warrants (HPAIW)	2023-2025	1,222.42%
Kingstone Companies (KINS)	2023-2025	1,071.21%
Sky Harbour Group Corporation WT (SKYH.WT)	2023-2025	1,070%