Carvana (CVNA) has had the highest return between 2023 and 2025 by a large-cap US stock, returning 5,221.8%.

ASSET	YEARS	% RETURN
Carvana (CVNA)	2023-2025	5,221.83%
Applovin (APP)	2023-2025	3,306.75%
MicroStrategy (MSTR)	2023-2025	2,211.39%
Palantir Technologies Inc Class A Common Stock (PLTR)	2023-2025	1,440.43%
Celestica (CLS)	2023-2025	1,169.17%
Vertiv (VRT)	2023-2025	760.38%
NVIDIA (NVDA)	2023-2025	741.09%
Vistra Energy (VST)	2023-2025	667.02%
Grupo Financiero Galicia SA ADR (GGAL)	2023-2025	666.98%
Spotify Technology (SPOT)	2023-2025	664.53%
Coinbase Global (COIN)	2023-2025	654.01%
Rocket Lab USA (RKLB)	2023-2025	642.86%
Fortress Transp & Infra Inv (FTAI)	2023-2025	626.29%
Robinhood Markets (HOOD)	2023-2025	556.17%
Reddit (RDDT)	2023-2025	550.47%
Affirm (AFRM)	2023-2025	526.75%
Credo Technology (CRDO)	2023-2025	484.79%
Facebook (META)	2023-2025	476.1%
Aurora Innovation (AUR)	2023-2025	466.14%
Duolingo (DUOL)	2023-2025	451.1%
Royal Caribbean Cruises (RCL)	2023-2025	430.5%
Sprouts Farmers Market LLC (SFM)	2023-2025	422.45%
Summit Therapeutics (SMMT)	2023-2025	378.8%
Flex (FLEX)	2023-2025	338.54%
Natera (NTRA)	2023-2025	335.32%

Large-cap stocks are treated as having a market cap of $10B+.