Monster Beverage (MNST) had the highest return between 2004 and 2006 by a large-cap US stock, returning 3,093.1%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2004-2006	3,093.06%
Banco Bradesco SA ADR (BBD)	2004-2006	933.14%
Tenaris SA ADR (TS)	2004-2006	714.53%
Apple (AAPL)	2004-2006	687.51%
CME (CME)	2004-2006	617.56%
Bancolombia SA ADR (CIB)	2004-2006	568.37%
Suzano Papel e Celulose SA ADR (SUZ)	2004-2006	511.16%
Intuitive Surgical (ISRG)	2004-2006	460.82%
Clean Harbors (CLH)	2004-2006	444.54%
Hologic (HOLX)	2004-2006	440.65%
ArcelorMittal SA ADR (MT)	2004-2006	440.29%
Illumina (ILMN)	2004-2006	438.49%
CBRE Group Inc Class A (CBRE)	2004-2006	424.21%
America Movil SAB de CV ADR (AMX)	2004-2006	413.92%
Cheniere Energy (LNG)	2004-2006	393.93%
Akamai Technologies (AKAM)	2004-2006	389.59%
Vale SA ADR (VALE)	2004-2006	367.8%
Alphabet Inc Class A (GOOGL)	2004-2006	360.43%
Jones Lang LaSalle (JLL)	2004-2006	348.88%
Valero Energy (VLO)	2004-2006	342.16%
Texas Pacific Land Trust (TPL)	2004-2006	340.97%
Canadian Natural Resources (CNQ)	2004-2006	328.91%
Nucor (NUE)	2004-2006	321.75%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2004-2006	321.15%
Cameco (CCJ)	2004-2006	320.52%

Large-cap stocks are treated as having a market cap of $10B+.