Summit Therapeutics (SMMT) had the best day last year by a large-cap US stock on May 30, returning 283.2%.

ASSET	DATE	% RETURN
Summit Therapeutics (SMMT)	5/30/2024	283.16%
GameStop (GME)	6/6/2024	47.45%
GameStop (GME)	5/3/2024	32.61%
Reddit (RDDT)	3/25/2024	26.99%
Summit Therapeutics (SMMT)	5/29/2024	25.43%
GameStop (GME)	6/11/2024	24.96%
MicroStrategy (MSTR)	8/5/2024	24.47%
Arm Holdings plc American Depositary Shares (ARM)	2/12/2024	23.98%
Aurora Innovation (AUR)	9/24/2024	21.86%
Super Micro Computer (SMCI)	1/19/2024	21.81%
Arm Holdings plc American Depositary Shares (ARM)	2/8/2024	20.63%
GameStop (GME)	6/5/2024	20.04%
Affirm (AFRM)	11/11/2024	19.99%
Summit Therapeutics (SMMT)	5/1/2024	19.9%
Summit Therapeutics (SMMT)	9/9/2024	19.18%
Summit Therapeutics (SMMT)	9/10/2024	19.17%
First Solar (FSLR)	5/22/2024	18.01%
Aurora Innovation (AUR)	7/15/2024	17.9%
Texas Pacific Land Trust (TPL)	6/10/2024	17.69%
BioNTech SE (BNTX)	9/13/2024	17.43%
Coinbase Global (COIN)	8/5/2024	16.95%
Aurora Innovation (AUR)	8/23/2024	16.85%
Rocket Companies (RKT)	8/2/2024	16.55%
Applovin (APP)	11/8/2024	16.43%
Insmed (INSM)	5/29/2024	16.41%

Large-cap stocks are treated as having a market cap of $10B+.