Brainstorm Cell Therapeutics (BCLI) had the highest return between 2000 and 2003 by a US stock, returning 4,605.9%.

ASSET	YEARS	% RETURN
Brainstorm Cell Therapeutics (BCLI)	2000-2003	4,605.93%
MEDIFAST (MED)	2000-2003	4,002.08%
Versus Systems Inc. (VS)	2000-2003	3,900%
TherapeuticsMD (TXMD)	2000-2003	3,650%
China Yuchai International (CYD)	2000-2003	3,495%
Xcel Brands (XELB)	2000-2003	3,399.99%
Odyssey Marine Exploration (OMEX)	2000-2003	1,900%
Flexible Solutions International (FSI)	2000-2003	1,884.08%
American Vanguard (AVD)	2000-2003	1,526.47%
Houston American Energy (HUSA)	2000-2003	1,360.09%
Hovnanian Enterprises (HOV)	2000-2003	1,279.17%
CarMax (KMX)	2000-2003	1,274.67%
Future Fintech (FTFT)	2000-2003	1,200%
John B Sanfilippo & Son (JBSS)	2000-2003	1,175.99%
Avadel Pharmaceuticals (AVDL)	2000-2003	1,160.71%
USANA Health Sciences (USNA)	2000-2003	1,159.47%
BJs Restaurants (BJRI)	2000-2003	1,156.47%
Meritage (MTH)	2000-2003	1,133.7%
Axon Enterprise (AXON)	2000-2003	1,076.79%
SunOpta (STKL)	2000-2003	1,036%
Amedisys (AMED)	2000-2003	1,002.6%
Cal-Maine Foods (CALM)	2000-2003	964.53%
FTI Consulting (FCN)	2000-2003	951.66%
Idaho Strategic Resources (IDR)	2000-2003	940%
Companhia Siderurgica Nacional ADR (SID)	2000-2003	933.65%