Tectonic Therapeutic (TECX) has had the highest return between 2016 and 2024 by a US stock, returning 3,370,566.7%.

ASSET	YEARS	% RETURN
Tectonic Therapeutic (TECX)	2016-2024	3,370,566.67%
Gorilla Technology (GRRR)	2016-2024	1,367,900%
Cadrenal Therapeutics, Inc Common Stock (CVKD)	2016-2024	984,566.67%
Clene (CLNN)	2016-2024	416,566.67%
AppTech Payments Corp Warrant (APCXW)	2016-2024	189,900%
Asset Entities Inc Class B Common Stock (ASST)	2016-2024	148,466.67%
Immatics (IMTX)	2016-2024	141,900%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2016-2024	101,787.5%
MGO Global Inc Common Stock (MGOL)	2016-2024	90,920%
Freedom (FRHC)	2016-2024	87,120%
Shuttle Pharmaceuticals (SHPH)	2016-2024	85,566.67%
Zhihu Inc ADR (ZH)	2016-2024	49,763.01%
Bragg Gaming (BRAG)	2016-2024	38,072.04%
Alarum Technologies (ALAR)	2016-2024	32,053.39%
NVIDIA (NVDA)	2016-2024	17,696.67%
authID (AUID)	2016-2024	12,206.16%
Quantum Computing (QUBT)	2016-2024	12,110.71%
TSS, Inc Common Stock (TSSI)	2016-2024	11,877.78%
Applied Digital (APLD)	2016-2024	11,143.59%
SilverCrest Metals (SILV)	2016-2024	8,102.15%
Metalla Royalty & Streaming (MTA)	2016-2024	8,067.2%
Agape ATP Corporation Common Stock (ATPC)	2016-2024	7,966.67%
Azitra (AZTR)	2016-2024	7,185.71%
XORTX Therapeutics (XRTX)	2016-2024	6,912.58%
Zivo Bioscience (ZIVO)	2016-2024	6,836.6%