Tectonic Therapeutic (TECX) has had the highest return between 2012 and 2024 by a US stock, returning 3,370,566.7%.

ASSET	YEARS	% RETURN
Tectonic Therapeutic (TECX)	2012-2024	3,370,566.67%
Gorilla Technology (GRRR)	2012-2024	1,367,900%
Scienture (SCNX)	2012-2024	1,069,471.43%
Cadrenal Therapeutics, Inc Common Stock (CVKD)	2012-2024	984,566.67%
Bragg Gaming (BRAG)	2012-2024	591,566.67%
Clene (CLNN)	2012-2024	416,566.67%
iCoreConnect Inc Common stock (ICCT)	2012-2024	286,900%
Shuttle Pharmaceuticals (SHPH)	2012-2024	192,650%
AppTech Payments Corp Warrant (APCXW)	2012-2024	189,900%
QXO (QXO)	2012-2024	176,079.78%
Asset Entities Inc Class B Common Stock (ASST)	2012-2024	148,466.67%
Immatics (IMTX)	2012-2024	141,900%
Helport AI Limited Ordinary Shares (HPAI)	2012-2024	133,677.78%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2012-2024	101,787.5%
MGO Global Inc Common Stock (MGOL)	2012-2024	90,920%
Zhihu Inc ADR (ZH)	2012-2024	49,763.01%
authID (AUID)	2012-2024	49,420%
Xpel (XPEL)	2012-2024	44,988.89%
NVIDIA (NVDA)	2012-2024	42,663.04%
Celsius (CELH)	2012-2024	38,985.71%
American Lithium Corp Common Stock (AMLI)	2012-2024	32,125%
Alarum Technologies (ALAR)	2012-2024	32,053.39%
Tesla (TSLA)	2012-2024	23,861.02%
Applied Digital (APLD)	2012-2024	14,516.67%
Axon Enterprise (AXON)	2012-2024	11,946.76%