Since 2020, the Los Angeles Dodgers have the most wins by a team, with 458 wins.

Interpreted as:

most regular-season wins by an MLB team since 2020

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	458	250	.647	708	24,059	3,774	6,117	1,264	107	1,049	3,630	2,694	339	5,948	433	91	27,375	10,742	2,420	53	230	127	424	.254	.335	.446	.781
2	Braves	417	290	.590	707	24,024	3,578	6,133	1,263	72	1,105	3,443	2,281	281	6,274	370	101	26,799	10,855	2,440	45	168	93	470	.255	.325	.452	.777
3	Astros	408	299	.577	707	24,091	3,446	6,204	1,230	77	916	3,317	2,287	286	5,258	358	105	26,909	10,336	2,223	50	195	93	549	.258	.327	.429	.756
4	Rays	405	303	.572	708	23,794	3,276	5,773	1,216	112	818	3,109	2,335	330	6,450	569	182	26,644	9,667	2,146	29	156	71	402	.243	.317	.406	.723
5	Yankees	400	308	.565	708	23,441	3,321	5,606	989	57	1,026	3,163	2,721	259	6,106	380	114	26,648	9,787	2,072	48	179	99	583	.239	.323	.418	.740
6	Brewers	395	313	.558	708	23,557	3,215	5,600	1,095	89	830	3,078	2,572	307	6,382	539	132	26,649	9,363	2,014	58	155	93	513	.238	.319	.397	.716
7	Phillies	382	326	.540	708	23,885	3,367	6,021	1,183	116	903	3,229	2,325	278	6,096	506	111	26,754	10,145	2,202	87	179	111	476	.252	.323	.425	.748
8	Padres	380	328	.537	708	23,751	3,271	5,901	1,183	83	823	3,134	2,475	267	5,518	471	134	26,789	9,719	2,089	115	181	106	520	.248	.324	.409	.733
9	Mariners	380	328	.537	708	23,489	3,075	5,408	1,060	60	851	2,950	2,457	418	6,662	455	125	26,567	9,141	1,971	39	164	57	448	.230	.312	.389	.701
10	Blue Jays	378	330	.534	708	24,026	3,340	6,164	1,268	74	894	3,205	2,259	265	5,504	352	111	26,753	10,262	2,236	44	159	63	542	.257	.325	.427	.752
11	Giants	376	332	.531	708	23,745	3,186	5,727	1,155	100	856	3,053	2,404	319	6,366	274	76	26,723	9,650	2,111	73	182	101	508	.241	.317	.406	.723
12	Guardians	375	332	.530	707	23,672	3,033	5,767	1,156	105	698	2,874	2,079	311	5,364	552	136	26,332	9,227	1,959	79	191	128	479	.244	.311	.390	.700
13	Mets	368	340	.520	708	23,595	3,179	5,849	1,106	88	855	3,044	2,241	450	5,820	360	95	26,524	9,696	2,049	84	154	80	508	.248	.323	.411	.734
14	Cardinals	367	339	.520	706	23,616	3,109	5,838	1,145	83	820	2,984	2,268	325	5,688	395	115	26,477	9,609	2,048	79	189	73	462	.247	.319	.407	.726
15	Twins	356	352	.503	708	23,823	3,214	5,823	1,194	85	913	3,063	2,296	354	6,246	257	80	26,695	9,926	2,192	41	181	65	527	.244	.318	.417	.735
16	Red Sox	353	355	.499	708	24,256	3,379	6,254	1,450	91	831	3,223	2,156	289	6,246	379	120	26,921	10,379	2,372	44	176	98	510	.258	.324	.428	.752
17	Orioles	352	356	.497	708	23,937	3,200	5,890	1,214	108	861	3,074	2,092	284	6,087	380	117	26,557	9,903	2,183	68	176	56	417	.246	.312	.414	.726
18	Cubs	345	363	.487	708	23,594	3,182	5,687	1,094	124	809	3,022	2,354	375	6,365	504	148	26,587	9,456	2,027	92	172	72	489	.241	.318	.401	.718
19	Reds	335	373	.473	708	23,469	3,159	5,607	1,131	100	840	3,021	2,296	409	6,348	520	159	26,415	9,458	2,071	84	157	47	487	.239	.316	.403	.719
20	Tigers	330	376	.467	706	23,567	2,846	5,567	1,038	152	678	2,738	2,001	222	6,428	315	102	26,015	8,943	1,868	45	180	39	460	.236	.300	.379	.679
21	Diamondbacks	324	384	.458	708	23,795	3,282	5,822	1,216	148	752	3,108	2,358	292	5,779	454	108	26,796	9,590	2,116	134	217	71	466	.245	.318	.403	.721
22	Rangers	318	390	.449	708	23,886	3,120	5,754	1,075	86	836	2,969	2,145	237	6,075	459	128	26,476	9,509	1,997	44	164	62	427	.241	.308	.398	.706
23	Marlins	313	395	.442	708	23,697	2,775	5,727	1,057	94	678	2,639	1,910	265	6,216	490	136	26,112	9,006	1,829	86	154	76	530	.242	.304	.380	.684
24	Angels	312	396	.441	708	23,726	3,014	5,671	1,056	103	861	2,880	2,152	303	6,363	382	142	26,411	9,516	2,020	81	149	102	484	.239	.309	.401	.710
25	White Sox	311	397	.439	708	23,899	2,936	5,837	1,131	59	739	2,807	1,925	270	6,056	311	93	26,312	9,303	1,929	75	143	47	548	.244	.306	.389	.695