Since 1980, the New York Yankees have the most wins by a team, with 4,006 wins.

Interpreted as:

most MLB team regular-season wins since 1980

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	4,006	3,079	.565	7,088	242,878	35,452	64,487	11,901	1,010	8,592	33,771	26,250	2,321	45,834	4,364	1,649	274,935	104,184	21,503	1,353	2,133	1,653	5,915	.266	.340	.429	.769
2	Dodgers	3,878	3,217	.547	7,097	240,965	31,253	61,891	11,069	1,220	6,992	29,604	23,437	2,056	47,255	4,872	2,036	271,345	96,376	19,281	2,990	1,897	2,154	5,090	.257	.326	.400	.726
3	Braves	3,801	3,280	.537	7,084	241,012	32,039	62,172	11,769	1,158	7,440	30,392	23,628	1,908	47,975	4,124	1,963	271,170	98,577	20,367	2,800	1,822	2,110	5,397	.258	.327	.409	.736
4	Red Sox	3,795	3,299	.535	7,095	246,051	35,398	66,887	14,115	1,245	7,598	33,628	25,032	2,306	45,774	3,313	1,468	276,964	106,286	22,958	1,409	2,166	1,862	6,025	.272	.342	.432	.774
5	Cardinals	3,774	3,309	.533	7,088	240,814	32,030	62,882	11,913	1,433	6,396	30,282	23,767	2,179	46,279	5,478	2,205	271,600	96,849	19,742	2,824	2,016	2,222	5,285	.261	.330	.402	.733
6	Astros	3,674	3,422	.518	7,097	241,391	31,586	62,228	12,023	1,377	6,730	29,905	23,245	2,292	47,158	5,247	2,184	271,547	97,195	20,130	2,624	1,995	2,041	5,237	.258	.326	.403	.729
7	Giants	3,633	3,464	.512	7,098	241,420	31,022	61,586	11,617	1,509	6,596	29,331	23,412	2,008	48,065	4,085	1,986	271,667	96,009	19,722	2,891	1,936	2,479	5,240	.255	.324	.398	.721
8	Athletics	3,619	3,475	.510	7,094	241,074	32,714	60,975	11,649	1,056	7,561	30,974	25,364	2,186	47,924	4,549	1,760	272,238	97,419	20,266	1,529	2,085	1,278	5,538	.253	.327	.404	.731
9	Blue Jays	3,608	3,483	.509	7,094	243,369	33,223	63,437	12,797	1,377	7,937	31,559	22,677	2,338	46,681	4,394	1,796	271,668	102,799	22,111	1,273	2,011	1,317	5,503	.261	.327	.422	.750
10	Guardians	3,594	3,487	.508	7,083	242,616	33,470	64,144	12,388	1,224	7,158	31,714	23,868	2,237	45,265	4,934	2,009	272,694	100,454	20,770	1,754	2,219	1,541	5,605	.264	.333	.414	.747
11	Mets	3,578	3,507	.505	7,087	240,331	30,826	61,003	11,560	1,217	6,780	29,205	23,195	2,228	47,713	4,704	1,878	270,346	95,337	19,557	2,653	1,939	2,201	5,135	.254	.323	.397	.720
12	Angels	3,567	3,528	.503	7,095	242,149	32,404	63,032	11,467	1,178	7,169	30,644	22,608	2,142	45,402	4,453	2,112	270,905	98,362	19,814	2,037	1,969	1,623	5,593	.260	.326	.406	.733
13	Phillies	3,548	3,544	.500	7,095	242,119	31,720	61,897	11,936	1,554	6,881	30,029	24,109	2,182	49,599	4,849	1,616	272,764	97,584	20,371	2,473	1,881	2,219	5,037	.256	.326	.403	.729
14	Brewers	3,519	3,574	.496	7,095	241,609	32,315	62,243	11,987	1,373	7,266	30,682	23,099	2,379	48,826	4,931	2,044	271,355	98,774	20,626	2,298	1,970	1,723	5,306	.258	.326	.409	.735
15	White Sox	3,492	3,594	.493	7,092	241,650	32,381	62,926	11,472	1,309	7,408	30,808	21,902	2,215	45,795	4,501	2,028	269,795	99,240	20,189	1,991	2,037	1,412	5,476	.260	.325	.411	.736
16	Rangers	3,479	3,610	.491	7,093	243,623	33,933	64,290	12,181	1,282	7,904	32,179	22,628	2,108	47,790	4,327	1,906	272,073	102,747	21,367	1,663	2,051	1,442	5,375	.264	.329	.422	.751
17	Nationals	3,477	3,612	.490	7,092	240,175	30,265	61,337	12,238	1,430	6,337	28,546	22,324	2,203	47,407	5,607	2,197	269,467	95,446	20,005	2,898	1,867	2,199	5,156	.255	.322	.397	.720
18	Reds	3,465	3,629	.488	7,099	240,725	31,331	61,276	11,807	1,254	7,221	29,634	23,475	2,281	50,229	5,498	2,127	271,139	97,254	20,282	2,779	1,879	2,029	5,030	.255	.324	.404	.728
19	Cubs	3,460	3,622	.489	7,089	241,926	31,425	61,908	11,751	1,418	7,289	29,761	22,442	2,145	49,764	4,193	1,870	270,985	98,362	20,458	2,655	1,817	2,003	5,132	.256	.322	.407	.729
20	Twins	3,446	3,647	.486	7,095	243,444	32,442	64,180	12,534	1,487	6,603	30,663	22,234	2,200	45,451	3,907	1,868	271,328	99,497	20,624	1,392	2,058	1,478	5,836	.264	.328	.409	.737
21	Mariners	3,427	3,665	.483	7,094	242,135	31,700	62,216	11,692	1,136	7,343	30,127	23,044	2,258	47,362	4,652	2,001	271,093	98,209	20,171	1,734	1,922	1,572	5,280	.257	.325	.406	.731
22	Padres	3,425	3,675	.482	7,102	240,443	29,730	60,528	11,028	1,353	6,132	28,041	23,158	1,811	49,069	5,006	2,058	269,951	92,658	18,513	2,660	1,879	2,057	5,270	.252	.320	.385	.705
23	Orioles	3,409	3,675	.481	7,088	242,593	32,420	62,903	11,797	977	7,991	30,896	23,034	2,109	45,621	3,556	1,595	271,227	100,627	20,765	1,515	1,976	1,374	5,747	.259	.326	.415	.741
24	Tigers	3,399	3,691	.479	7,091	242,911	32,653	63,279	11,724	1,606	7,508	31,053	23,153	1,969	48,878	3,700	1,888	271,601	100,739	20,838	1,555	2,013	1,396	5,336	.261	.327	.415	.742
25	Royals	3,302	3,784	.466	7,087	242,806	31,120	63,867	12,168	1,732	5,886	29,441	20,077	2,103	43,809	5,412	2,105	268,791	97,157	19,786	1,722	2,083	1,353	5,462	.263	.322	.400	.722