The Edmonton Oilers lost their most games in a season in 1992-93, with 50 losses.

Interpreted as:

oilers worse season opener loss in a regular season

	TEAM	L	SEASON	GP	W	T	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Oilers	50	1992-93	84	26	8		60	.357			242	337	-95	15.9	77.2	27.94	10.3	33.76	.881
2	Oilers	47	2009-10	82	27		8	62	.378	8	6	206	278	-72	17.3	78.0	28.30	8.9	33.12	.898
3	Oilers	45	2010-11	82	25		12	62	.378	2	9	191	260	-69	14.5	76.9	26.68	8.7	31.67	.900
4	Oilers	45	1993-94	84	25	14		64	.381			261	305	-44	18.4	80.5	30.35	10.2	34.42	.895
5	Oilers	44	2014-15	82	24		14	62	.378	5	7	193	276	-83	17.7	76.7	28.43	8.3	30.05	.888
6	Oilers	44	2013-14	82	29		9	67	.409	4	3	199	267	-68	17.0	82.1	26.93	9.0	32.88	.901
7	Oilers	44	1995-96	82	30	8		68	.415			240	304	-64	15.9	80.8	29.99	9.8	30.40	.878
8	Oilers	43	2015-16	82	31		8	70	.427	4	3	199	242	-43	18.1	81.1	29.10	8.3	31.07	.905
9	Oilers	43	2006-07	82	32		7	71	.433	3	3	192	245	-53	14.2	84.6	26.74	8.8	29.74	.900
10	Oilers	40	2017-18	82	36		6	78	.476	5	1	229	262	-33	14.8	76.7	33.41	8.4	32.12	.901
11	Oilers	40	2011-12	82	32		10	74	.451	5	7	207	232	-25	20.6	82.4	26.66	9.5	30.71	.908
12	Oilers	39	1979-80	80	28	13		69	.431			301	322	-21	22.3	76.4	28.36	13.3	30.78	.869
13	Oilers	38	2018-19	82	35		9	79	.482	3	3	229	271	-42	21.2	74.8	29.17	9.6	31.70	.896
14	Oilers	37	1998-99	82	33	12		78	.476			230	226	4	14.4	82.1	29.22	9.6	27.11	.898
15	Oilers	37	1997-98	82	35	10		80	.488			215	224	-9	15.9	83.7	28.67	9.1	28.21	.903
16	Oilers	37	1996-97	82	36	9		81	.494			252	247	5	18.0	82.5	30.74	10.0	31.17	.903
17	Oilers	37	1990-91	80	37	6		80	.500			272	272	0	17.5	79.4	27.59	12.3	30.35	.888
18	Oilers	35	2008-09	82	38		9	85	.518	6	4	228	244	-16	16.9	77.5	28.09	9.9	32.54	.909
19	Oilers	35	2007-08	82	41		6	88	.537	15	4	220	247	-27	16.6	84.7	26.29	10.2	31.38	.904
20	Oilers	35	1980-81	80	29	16		74	.463			328	327	1	22.2	75.4	29.84	13.7	29.51	.861
21	Oilers	34	1991-92	80	36	10		82	.513			295	297	-2	18.6	78.0	27.71	13.3	31.06	.880
22	Oilers	34	1988-89	80	38	8		84	.525			325	306	19	19.8	82.8	27.81	14.6	30.40	.874
23	Oilers	29	2003-04	82	36	12	5	89	.543			221	208	13	13.0	81.1	28.44	9.5	26.52	.904
24	Oilers	28	2005-06	82	41		13	95	.579	7	9	249	242	7	18.1	84.1	29.78	10.2	25.55	.884
25	Oilers	28	2001-02	82	38	12	4	92	.561			205	182	23	15.3	85.6	27.51	9.1	25.85	.914