Marc-Andre Fleury has the most career wins by an active goalie, with 575 wins.

Interpreted as:

NHL active goalies most career regular-season wins

	NAME	W	GP	GS	L	T	OTL	SA	SV	SV%	GA	GAA	SHO	MIN
1	Marc-Andre Fleury M. Fleury	575	1,051	1,017	339	2	95	29,821	27,188	.912	2,633	2.60	76	60668
2	Sergei Bobrovsky S. Bobrovsky	429	754	740	243	0	57	21,796	19,928	.914	1,868	2.58	49	43525
3	Jonathan Quick J. Quick	404	804	786	290	0	88	21,670	19,731	.911	1,939	2.49	63	46660
4	Andrei Vasilevskiy A. Vasilevskiy	331	540	530	163	0	35	16,107	14,772	.917	1,335	2.52	40	31792
5	Connor Hellebuyck C. Hellebuyck	322	568	558	185	0	44	17,066	15,660	.918	1,406	2.56	45	32999
6	Frederik Andersen F. Andersen	308	517	503	135	0	53	15,007	13,734	.915	1,273	2.56	28	29886
7	Semyon Varlamov S. Varlamov	289	621	593	232	0	71	18,625	17,053	.916	1,572	2.65	41	35629
8	Cam Talbot C. Talbot	266	533	508	195	0	47	15,392	14,043	.912	1,349	2.66	33	30424
9	Jacob Markstrom J. Markstrom	241	534	517	212	0	63	15,106	13,720	.908	1,386	2.70	24	30758
10	James Reimer J. Reimer	225	525	479	187	0	65	15,365	13,977	.910	1,388	2.89	31	28834
11	Darcy Kuemper D. Kuemper	209	439	418	146	0	53	12,366	11,311	.915	1,055	2.54	36	24924
12	Jake Allen J. Allen	208	460	436	184	0	43	12,862	11,671	.907	1,191	2.76	28	25932
13	John Gibson J. Gibson	204	506	494	217	0	63	15,420	14,033	.910	1,387	2.89	24	28803
14	Juuse Saros J. Saros	202	408	391	150	0	38	12,175	11,130	.914	1,045	2.68	27	23404
15	Petr Mrazek P. Mrazek	180	428	397	176	0	40	12,038	10,904	.906	1,134	2.85	26	23887
16	Jordan Binnington J. Binnington	173	336	327	116	0	36	9,644	8,743	.907	901	2.78	18	19476
17	Philipp Grubauer P. Grubauer	166	370	337	139	0	33	9,776	8,877	.908	899	2.65	22	20352
18	Linus Ullmark L. Ullmark	163	291	281	87	0	26	8,560	7,850	.917	710	2.54	12	16756
19	Igor Shesterkin I. Shesterkin	162	274	269	88	0	22	8,109	7,439	.917	670	2.52	21	15932
20	Tristan Jarry T. Jarry	152	293	281	97	0	31	8,324	7,569	.909	755	2.75	21	16480
21	Alexandar Georgiev A. Georgiev	151	303	288	108	0	26	8,739	7,892	.903	847	2.99	15	17011
22	Jake Oettinger J. Oettinger	149	251	242	66	0	27	6,904	6,296	.912	608	2.52	12	14451
23	Thatcher Demko T. Demko	126	242	236	89	0	20	7,334	6,675	.910	659	2.80	9	14108
24	Joonas Korpisalo J. Korpisalo	126	303	274	117	0	32	8,574	7,721	.901	853	3.05	7	16787
25	Ilya Sorokin I. Sorokin	125	253	248	89	0	36	7,561	6,927	.916	634	2.58	22	14756