4 players were tied for the most interceptions in 2022, with 6 interceptions. The first three are Justin Simmons, Minkah Fitzpatrick and C.J. Gardner-Johnson.
| NAME | INT | SEASON | TM | GP | TKL | AST | COMB | SCK | SCKY | INT YDS | INT TD | FF | FR | FR TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Simmons | 6 | 2022 |  DEN | 12 | 42 | 27 | 69 | 0.0 | 0 | 51 | 0 | 3 | 1 | 0 |
| 2 | | M. Fitzpatrick | 6 | 2022 |  PIT | 15 | 56 | 40 | 96 | 0.0 | 0 | 94 | 1 | 0 | 0 | 0 |
| 3 | | C.J. Gardner-Johnson | 6 | 2022 |  PHI | 12 | 61 | 6 | 67 | 1.0 | 11 | 54 | 0 | 0 | 0 | 0 |
| 4 | | R. Woolen | 6 | 2022 |  SEA | 17 | 46 | 17 | 63 | 0.0 | 0 | 47 | 1 | 0 | 3 | 0 |
| 5 | | T. Gipson Sr. | 5 | 2022 |  SF | 17 | 43 | 18 | 61 | 0.5 | 2.5 | 141 | 0 | 0 | 0 | 0 |
| 6 |  | P. Peterson | 5 | 2022 |  MIN | 17 | 56 | 10 | 66 | 0.0 | 0 | 92 | 0 | 0 | 0 | 0 |
| 7 | | H. Smith | 5 | 2022 | MIN | 14 | 66 | 19 | 85 | 0.0 | 0 | 58 | 0 | 1 | 0 | 0 |
| 8 | | J. Alexander | 5 | 2022 |  GB | 16 | 43 | 13 | 56 | 0.0 | 0 | 59 | 0 | 0 | 0 | 0 |
| 9 | | J. Pitre | 5 | 2022 |  HOU | 17 | 99 | 48 | 147 | 1.0 | 8 | 57 | 0 | 0 | 1 | 0 |
| 10 | | D. Bland | 5 | 2022 |  DAL | 17 | 38 | 16 | 54 | 0.0 | 0 | 19 | 0 | 0 | 0 | 0 |
| 11 | | D. McCourty | 4 | 2022 |  NE | 17 | 54 | 17 | 71 | 0.0 | 0 | 66 | 0 | 0 | 1 | 0 |
| 12 | | J. Poyer | 4 | 2022 |  BUF | 12 | 44 | 19 | 63 | 0.0 | 0 | 6 | 0 | 1 | 0 | 0 |
| 13 | | Q. Diggs | 4 | 2022 | SEA | 17 | 50 | 21 | 71 | 0.0 | 0 | 70 | 0 | 1 | 0 | 0 |
| 14 | | V. Bell | 4 | 2022 |  CIN | 16 | 52 | 25 | 77 | 1.0 | 6.5 | 56 | 0 | 2 | 1 | 0 |
| 15 | | J. Jones | 4 | 2022 | NE | 16 | 56 | 13 | 69 | 0.0 | 0 | 89 | 1 | 3 | 0 | 0 |
| 16 | | K. Byard III | 4 | 2022 |  TEN | 17 | 69 | 39 | 108 | 0.0 | 0 | 57 | 0 | 0 | 0 | 0 |
| 17 |  | J. Ramsey | 4 | 2022 |  LAR | 17 | 64 | 24 | 88 | 2.0 | 17 | 53 | 0 | 3 | 1 | 0 |
| 18 | | M. Williams | 4 | 2022 |  BAL | 10 | 44 | 17 | 61 | 0.0 | 0 | 33 | 0 | 0 | 1 | 0 |
| 19 | | R. Douglas | 4 | 2022 | GB | 17 | 69 | 16 | 85 | 1.0 | 0 | 26 | 0 | 1 | 0 | 0 |
| 20 | | E. Jackson | 4 | 2022 |  CHI | 12 | 59 | 21 | 80 | 0.0 | 0 | 44 | 0 | 2 | 0 | 0 |
| 21 | | J. Bates III | 4 | 2022 | CIN | 16 | 38 | 33 | 71 | 0.0 | 0 | 28 | 0 | 1 | 0 | 0 |
| 22 | | L. Wallace | 4 | 2022 | PIT | 15 | 33 | 15 | 48 | 0.0 | 0 | 6 | 0 | 0 | 0 | 0 |
| 23 | | G. Delpit | 4 | 2022 |  CLE | 17 | 72 | 33 | 105 | 0.0 | 0 | 36 | 0 | 0 | 0 | 0 |
| 24 | | D. Forrest | 4 | 2022 |  WAS | 17 | 56 | 32 | 88 | 0.0 | 0 | 1 | 0 | 2 | 1 | 0 |
| 25 | | T. Hufanga | 4 | 2022 | SF | 17 | 66 | 31 | 97 | 2.0 | 12 | 61 | 1 | 2 | 0 | 0 |
StatMuse has season-level data for interceptions going back to the 1940 season.
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