Peyton Manning had the most wins by a quarterback in his first 12 seasons, with 131 wins.

Interpreted as:

most regular-season wins in qbs first 12 seasons

	NAME	W	GP	CMP	ATT	PCT	YDS	AVG	YDS/G	TD	INT	RATE	TD%	INT%	SCK	SCKY
1	Peyton Manning P. Manning	131	192	4,232	6,531	64.8	50,128	7.7	261.1	366	181	95.2	5.6	2.8	215	1,392
2	Tom Brady T. Brady	124	161	3,397	5,321	63.8	39,979	7.5	248.3	300	115	96.4	5.6	2.2	276	1,712
3	Brett Favre B. Favre	117	177	3,652	5,992	60.9	42,285	7.1	238.9	314	188	86.7	5.2	3.1	348	2,261
4	Russell Wilson R. Wilson	115	188	3,668	5,665	64.7	43,653	7.7	232.2	334	106	100.0	5.9	1.9	527	3,464
5	Ben Roethlisberger B. Roethlisberger	114	171	3,476	5,423	64.1	42,995	7.9	251.4	272	147	94.0	5.0	2.7	439	2,867
6	Matt Ryan M. Ryan	109	189	4,460	6,817	65.4	51,186	7.5	270.8	321	147	94.6	4.7	2.2	369	2,449
7	Joe Montana J. Montana	109	166	2,914	4,579	63.6	34,998	7.6	210.8	242	123	93.4	5.3	2.7
8	Dan Marino D. Marino	107	172	3,604	6,049	59.6	45,173	7.5	262.6	328	185	88.2	5.4	3.1	178	1,270
9	Ken Stabler K. Stabler	107	159	1,944	3,223	60.3	24,268	7.5	152.6	177	189	77.6	5.5	5.9
10	John Elway J. Elway	105	174	3,030	5,384	56.3	37,736	7.0	216.9	199	177	76.8	3.7	3.3	416	3,073
11	Joe Theismann J. Theismann	105	167	2,044	3,602	56.7	25,206	7.0	150.9	160	138	77.4	4.4	3.8
12	Terry Bradshaw T. Bradshaw	104	158	1,893	3,653	51.8	26,144	7.2	165.5	193	199	70.0	5.3	5.4
13	Jim Kelly J. Kelly	101	160	2,874	4,779	60.1	35,467	7.4	221.7	237	175	84.4	5.0	3.7	323	2,427
14	Daryle Lamonica D. Lamonica	101	137	1,255	2,528	49.6	18,717	7.4	136.6	161	134	73.4	6.4	5.3
15	Drew Brees D. Brees	99	170	4,035	6,149	65.6	45,919	7.5	270.1	324	165	94.3	5.3	2.7	234	1,698
16	Jeff Hostetler J. Hostetler	99	152	1,357	2,338	58.0	16,430	7.0	108.1	94	71	80.5	4.0	3.0	207	1,159
17	Joe Flacco J. Flacco	98	171	3,670	5,932	61.9	40,067	6.8	234.3	218	141	84.1	3.7	2.4	359	2,554
18	Eli Manning E. Manning	98	185	3,695	6,227	59.3	44,187	7.1	238.8	294	199	83.5	4.7	3.2	307	2,137
19	Donovan McNabb D. McNabb	98	161	3,076	5,218	58.9	36,250	6.9	225.2	230	115	85.7	4.4	2.2	394	2,513
20	Johnny Unitas J. Unitas	98	153	2,261	4,097	55.2	33,021	8.1	215.8	252	189	82.9	6.2	4.6
21	Philip Rivers P. Rivers	95	164	3,462	5,339	64.8	41,447	7.8	252.7	281	135	95.5	5.3	2.5	326	1,990
22	Don Strock D. Strock	95	135	361	645	56.0	4,347	6.7	32.2	37	36	72.7	5.7	5.6
23	Troy Aikman T. Aikman	94	165	2,898	4,715	61.5	32,942	7.0	199.6	165	141	81.6	3.5	3.0	259	1,748
24	Roger Staubach R. Staubach	94	131	1,685	2,958	57.0	22,700	7.7	173.3	153	109	83.4	5.2	3.7
25	Aaron Rodgers A. Rodgers	93	142	3,034	4,657	65.1	36,827	7.9	259.3	297	72	104.1	6.4	1.5	341	2,163