Drew Brees had a passer rating of 98.7 with 80,358 yards, 571 touchdowns and 243 interceptions in 287 games in his career.
| NAME | SEASON | TM | GP | CMP | ATT | PCT | YDS | AVG | YDS/G | TD | INT | RATE | TD% | INT% | SCK | SCKY | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Brees | 2001 |  SD | 1 | 15 | 27 | 55.6 | 221 | 8.2 | 221.0 | 1 | 0 | 94.8 | 3.7 | 0.0 | 2 | 12 |
| 2 | | D. Brees | 2002 | SD | 16 | 320 | 526 | 60.8 | 3,284 | 6.2 | 205.3 | 17 | 16 | 76.9 | 3.2 | 3.0 | 24 | 180 |
| 3 | | D. Brees | 2003 | SD | 11 | 205 | 356 | 57.6 | 2,108 | 5.9 | 191.6 | 11 | 15 | 67.5 | 3.1 | 4.2 | 21 | 178 |
| 4 | | D. Brees | 2004 | SD | 15 | 262 | 400 | 65.5 | 3,159 | 7.9 | 210.6 | 27 | 7 | 104.8 | 6.8 | 1.8 | 18 | 131 |
| 5 | | D. Brees | 2005 | SD | 16 | 323 | 500 | 64.6 | 3,576 | 7.2 | 223.5 | 24 | 15 | 89.2 | 4.8 | 3.0 | 27 | 223 |
| 6 |  | D. Brees | 2006 |  NO | 16 | 356 | 554 | 64.3 | 4,418 | 8.0 | 276.1 | 26 | 11 | 96.2 | 4.7 | 2.0 | 18 | 105 |
| 7 | | D. Brees | 2007 | NO | 16 | 440 | 652 | 67.5 | 4,423 | 6.8 | 276.4 | 28 | 18 | 89.4 | 4.3 | 2.8 | 16 | 109 |
| 8 | | D. Brees | 2008 | NO | 16 | 413 | 635 | 65.0 | 5,069 | 8.0 | 316.8 | 34 | 17 | 96.2 | 5.4 | 2.7 | 13 | 92 |
| 9 | | D. Brees | 2009 | NO | 15 | 363 | 514 | 70.6 | 4,388 | 8.5 | 292.5 | 34 | 11 | 109.6 | 6.6 | 2.1 | 20 | 135 |
| 10 | | D. Brees | 2010 | NO | 16 | 448 | 658 | 68.1 | 4,620 | 7.0 | 288.8 | 33 | 22 | 90.9 | 5.0 | 3.3 | 25 | 185 |
| 11 | | D. Brees | 2011 | NO | 16 | 468 | 657 | 71.2 | 5,476 | 8.3 | 342.3 | 46 | 14 | 110.6 | 7.0 | 2.1 | 24 | 158 |
| 12 | | D. Brees | 2012 | NO | 16 | 422 | 670 | 63.0 | 5,177 | 7.7 | 323.6 | 43 | 19 | 96.3 | 6.4 | 2.8 | 26 | 190 |
| 13 | | D. Brees | 2013 | NO | 16 | 446 | 650 | 68.6 | 5,162 | 7.9 | 322.6 | 39 | 12 | 104.7 | 6.0 | 1.8 | 37 | 244 |
| 14 | | D. Brees | 2014 | NO | 16 | 456 | 659 | 69.2 | 4,952 | 7.5 | 309.5 | 33 | 17 | 97.0 | 5.0 | 2.6 | 29 | 186 |
| 15 | | D. Brees | 2015 | NO | 15 | 428 | 627 | 68.3 | 4,870 | 7.8 | 324.7 | 32 | 11 | 101.0 | 5.1 | 1.8 | 31 | 235 |
| 16 | | D. Brees | 2016 | NO | 16 | 471 | 673 | 70.0 | 5,208 | 7.7 | 325.5 | 37 | 15 | 101.7 | 5.5 | 2.2 | 27 | 184 |
| 17 | | D. Brees | 2017 | NO | 16 | 386 | 536 | 72.0 | 4,334 | 8.1 | 270.9 | 23 | 8 | 103.9 | 4.3 | 1.5 | 20 | 145 |
| 18 | | D. Brees | 2018 | NO | 15 | 364 | 489 | 74.4 | 3,992 | 8.2 | 266.1 | 32 | 5 | 115.7 | 6.5 | 1.0 | 17 | 121 |
| 19 | | D. Brees | 2019 | NO | 11 | 281 | 378 | 74.3 | 2,979 | 7.9 | 270.8 | 27 | 4 | 116.3 | 7.1 | 1.1 | 12 | 89 |
| 20 | | D. Brees | 2020 | NO | 12 | 275 | 390 | 70.5 | 2,942 | 7.5 | 245.2 | 24 | 6 | 106.4 | 6.2 | 1.5 | 13 | 89 |
| Average | 14.4 | 357.1 | 527.6 | 67.7 | 4017.9 | 7.6 | 280.0 | 28.6 | 12.2 | 98.7 | 5.4 | 2.3 | 21.0 | 149.6 | ||||
| Total | 287 | 7,142 | 10,551 | 67.7 | 80,358 | 7.6 | 280.0 | 571 | 243 | 98.7 | 5.4 | 2.3 | 420 | 2,991 |
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