Derrick Henry has had 107 carries for 558 yards and has scored 9 touchdowns in 6 games versus the Bills in his career.
| NAME | DATE | TM | OPP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Henry | 10/7/2018 |  TEN | @ |  BUF | 56 | 11 | 5.1 | 0 | 0 | 0 | 1 | 0 | |
| 2 | | D. Henry | 10/6/2019 | TEN | vs | BUF | 78 | 20 | 3.9 | 1 | 0 | 0 | 0 | 0 | |
| 3 | | D. Henry | 10/13/2020 | TEN | vs | BUF | 57 | 19 | 3.0 | 2 | 6 | 1 | 2 | 6.0 | 0 |
| 4 | | D. Henry | 10/18/2021 | TEN | vs | BUF | 143 | 20 | 7.2 | 3 | 13 | 2 | 3 | 6.5 | 0 |
| 5 | | D. Henry | 9/19/2022 | TEN | @ | BUF | 25 | 13 | 1.9 | 1 | 0 | 0 | 0 | 0 | |
| 6 |  | D. Henry | 9/29/2024 |  BAL | vs | BUF | 199 | 24 | 8.3 | 1 | 10 | 3 | 3 | 3.3 | 1 |
| Average | 93.0 | 17.8 | 5.2 | 1.3 | 4.8 | 1.0 | 1.5 | 4.8 | 0.2 | ||||||
| Total | 558 | 107 | 5.2 | 8 | 29 | 6 | 9 | 4.8 | 1 |
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NFL 2024 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 8 | 2 | 0 | .800 |
 Commanders | 7 | 4 | 0 | .636 |
| NFC North | W | L | T | PCT |
 Lions | 9 | 1 | 0 | .900 |
 Vikings | 8 | 2 | 0 | .800 |
| NFC South | W | L | T | PCT |
 Falcons | 6 | 5 | 0 | .545 |
 Buccaneers | 4 | 6 | 0 | .400 |
| NFC West | W | L | T | PCT |
 Cardinals | 6 | 4 | 0 | .600 |
 Rams | 5 | 5 | 0 | .500 |
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