The 2022 running backs for the Bills included Isaiah Bowser, James Cook, Reggie Gilliam, Nyheim Hines and Duke Johnson.
| NO. | NAME | POS | HEIGHT | WEIGHT | DOB | AGE | COLLEGE | ||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 0 |  | I. Bowser | RB | |||||
| 2 | 28 |  | J. Cook | RB | 5'11" | 190 | 9/25/1999 | 23 | Georgia |
| 3 | 41 | | R. Gilliam | RB | 6'1" | 255 | 8/20/1997 | Toledo | |
| 4 | 0 | | N. Hines | RB | 5'9" | 196 | 11/12/1996 | 26 | North Carolina State |
| 5 | 22 |  | D. Johnson | RB | 5'9" | 210 | 9/23/1993 | 29 | Miami (FL) |
| 6 | 25 | | T. Jones | RB | 6'0" | 195 | 7/26/1988 | 34 | Eastern Washington |
| 7 | 0 | | J. Mims | RB | 6/16/1999 | Fresno State | |||
| 8 | 20 |  | Z. Moss | RB | 5'10" | 215 | 12/15/1997 | 25 | Utah |
| 9 | 26 |  | D. Singletary | RB | 5'7" | 203 | 9/3/1997 | 25 | Florida Atlantic |
More Bills Stats
Team Rankings
PPG
30.9
2nd
OPP PPG
21.6
11th
RUSH YDS/G
131.2
9th
PASS YDS/G
231.6
17th
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 14 | 3 | 0 | .824 |
 Commanders | 12 | 5 | 0 | .706 |
| NFC North | W | L | T | PCT |
 Lions | 15 | 2 | 0 | .882 |
 Vikings | 14 | 3 | 0 | .824 |
| NFC South | W | L | T | PCT |
 Buccaneers | 10 | 7 | 0 | .588 |
 Falcons | 8 | 9 | 0 | .471 |
| NFC West | W | L | T | PCT |
 Rams | 10 | 7 | 0 | .588 |
 Seahawks | 10 | 7 | 0 | .588 |
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