Baker Mayfield has a passer rating of 63.2 with 677 yards, 2 touchdowns and 4 interceptions in 4 games versus the 49ers in his career.
| NAME | DATE | TM | OPP | CMP | ATT | PCT | YDS | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | B. Mayfield | 10/7/2019 |  CLE | @ |  SF | 8 | 22 | 36.4 | 100 | 4.5 | 0 | 2 | 13.4 | 0.0 | 9.1 | 4 | 42 |
| 2 |  | B. Mayfield | 10/9/2022 |  CAR | vs | SF | 20 | 36 | 55.6 | 215 | 6.0 | 0 | 1 | 61.7 | 0.0 | 2.8 | 4 | 16 |
| 3 |  | B. Mayfield | 11/19/2023 |  TB | @ | SF | 29 | 45 | 64.4 | 246 | 5.5 | 1 | 1 | 76.7 | 2.2 | 2.2 | 4 | 25 |
| 4 | | B. Mayfield | 11/10/2024 | TB | vs | SF | 18 | 29 | 62.1 | 116 | 4.0 | 1 | 0 | 82.0 | 3.4 | 0.0 | 2 | 11 |
| Average | 18.8 | 33.0 | 56.8 | 169.3 | 5.1 | 0.5 | 1.0 | 63.2 | 1.5 | 3.0 | 3.5 | 23.5 | ||||||
| Total | 75 | 132 | 56.8 | 677 | 5.1 | 2 | 4 | 63.2 | 1.5 | 3.0 | 14 | 94 |
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Bills 
Dolphins 
Steelers 
Ravens 
Texans 
Colts 
Chiefs 
Chargers | NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 7 | 2 | 0 | .778 |
 Commanders | 7 | 3 | 0 | .700 |
| NFC North | W | L | T | PCT |
 Lions | 8 | 1 | 0 | .889 |
 Vikings | 7 | 2 | 0 | .778 |
| NFC South | W | L | T | PCT |
 Falcons | 6 | 4 | 0 | .600 |
| Buccaneers | 4 | 6 | 0 | .400 |
| NFC West | W | L | T | PCT |
 Cardinals | 6 | 4 | 0 | .600 |
| 49ers | 5 | 4 | 0 | .556 |
LAR 
NYJ 
DAL 
TEN 
NE 
LV 
GB 
CHI 
JAX 
