The San Francisco 49ers have a 10-8 record against the spread against the AFC on the road since 2017.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/8/2017 | 0-1 |  SF | +105 | @ |  IND | -125 | L 23-26 | +1.5 | -1.5 (N) | 44 | +5 (O) | 2 | 23 | 402 | 447 | 28.6 | 100.0 |
| 2 | | 49ers | 12/10/2017 | 1-0 | SF | +108 | @ |  HOU | -118 | W 26-16 | -1.5 | +8.5 (Y) | 45.5 | -3.5 (U) | 2 | 20 | 416 | 311 | 18.2 | |
| 3 | | 49ers | 9/23/2018 | 0-1 | SF | +225 | @ |  KC | -245 | L 27-38 | +5.5 | -5.5 (N) | 53.5 | +11.5 (O) | 3 | 26 | 406 | 384 | 22.2 | 100.0 |
| 4 | | 49ers | 9/30/2018 | 1-0 | SF | +370 | @ |  LAC | -415 | L 27-29 | +9.5 | +7.5 (Y) | 46.5 | +9.5 (O) | 3 | 22 | 364 | 368 | 41.7 | |
| 5 | | 49ers | 9/15/2019 | 1-0 | SF | -110 | @ |  CIN | -110 | W 41-17 | +1 | +25 (Y) | 46.5 | +11.5 (O) | 5 | 27 | 571 | 316 | 55.6 | |
| 6 | | 49ers | 12/1/2019 | 1-0 | SF | +204 | @ |  BAL | -250 | L 17-20 | +5.5 | +2.5 (Y) | 45 | -8 (U) | 2 | 15 | 331 | 283 | 33.3 | 50.0 |
| 7 | | 49ers | 2/2/2020 | 0-1 | SF | +104 | @ | KC | -125 | L 20-31 | +1.5 | -9.5 (N) | 53 | -2 (U) | 2 | 21 | 351 | 397 | 37.5 | 0.0 |
| 8 | | 49ers | 9/20/2020 | 1-0 | SF | -325 | @ |  NYJ | +265 | W 31-13 | -7 | +11 (Y) | 41.5 | +2.5 (O) | 4 | 17 | 359 | 277 | 53.8 | |
| 9 | | 49ers | 10/25/2020 | 1-0 | SF | +131 | @ |  NE | -155 | W 33-6 | +3 | +30 (Y) | 44.5 | -5.5 (U) | 4 | 26 | 467 | 241 | 55.6 | |
| 10 | | 49ers | 11/21/2021 | 1-0 | SF | -290 | @ |  JAX | +233 | W 30-10 | -6.5 | +13.5 (Y) | 45.5 | -5.5 (U) | 3 | 25 | 333 | 200 | 50.0 | 100.0 |
| 11 | | 49ers | 12/12/2021 | 1-0 | SF | -128 | @ | CIN | +106 | W 26-23 | -1.5 | +1.5 (Y) | 49 | 0 (P) | 3 | 21 | 355 | 397 | 33.3 | |
| 12 | | 49ers | 12/23/2021 | 0-1 | SF | -175 | @ |  TEN | +147 | L 17-20 | -3.5 | -6.5 (N) | 45.5 | -8.5 (U) | 2 | 22 | 389 | 278 | 37.5 | 50.0 |
| 13 | | 49ers | 9/25/2022 | 0-1 | SF | -123 | @ |  DEN | +102 | L 10-11 | -1.5 | -2.5 (N) | 45 | -24 (U) | 1 | 13 | 267 | 261 | 10.0 | |
| 14 | | 49ers | 1/1/2023 | 0-1 | SF | -472 | @ |  LV | +359 | W 37-34 | -10 | -7 (N) | 41 | +30 (O) | 4 | 27 | 454 | 500 | 50.0 | |
| 15 | | 49ers | 9/10/2023 | 1-0 | SF | -121 | @ |  PIT | +102 | W 30-7 | -1.5 | +21.5 (Y) | 41.5 | -4.5 (U) | 3 | 22 | 391 | 239 | 46.2 | 100.0 |
| 16 | | 49ers | 10/15/2023 | 0-1 | SF | -507 | @ |  CLE | +379 | L 17-19 | -9.5 | -11.5 (N) | 36 | 0 (P) | 2 | 15 | 215 | 334 | 25.0 | |
| 17 | | 49ers | 11/12/2023 | 1-0 | SF | -172 | @ | JAX | +144 | W 34-3 | -3 | +28 (Y) | 44.5 | -7.5 (U) | 4 | 20 | 437 | 221 | 33.3 | 50.0 |
| 18 | | 49ers | 2/11/2024 | 0-1 | SF | -127 | @ | KC | +107 | L 22-25 | -2 | -5 (N) | 47 | 0 (P) | 2 | 23 | 382 | 455 | 25.0 | 100.0 |
| Average | 3.1 | 2.8 | 21.4 | 382.8 | 328.3 | 36.2 | 7.9 | |||||||||||||
| Total | 10-8 | 51 | 385 | 6,890 | 5,909 | 36.2 | 71.4 |
StatMuse has team, game-level data for spread records going back to the 1979 season.
More 49ers Stats
Team Rankings
PPG
23.6
13th
OPP PPG
23.6
21st
RUSH YDS/G
138.4
7th
PASS YDS/G
255.6
5th
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MIA 
CHI 
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NFL 2024 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 9 | 2 | 0 | .818 |
 Commanders | 8 | 5 | 0 | .615 |
| NFC North | W | L | T | PCT |
 Lions | 11 | 1 | 0 | .917 |
 Vikings | 10 | 2 | 0 | .833 |
| NFC South | W | L | T | PCT |
 Falcons | 6 | 6 | 0 | .500 |
 Buccaneers | 5 | 6 | 0 | .455 |
| NFC West | W | L | T | PCT |
 Seahawks | 7 | 5 | 0 | .583 |
 Cardinals | 6 | 6 | 0 | .500 |
Bills 
NO 
GB 
