James Harden had his most assists in a game against the Clippers on December 23, 2022, with 21 assists.

Interpreted as:

James Harden most assists in a regular-season game

	NAME	AST	DATE	TM		OPP	MIN	PTS	REB	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	James Harden J. Harden	21	12/23/2022	PHI	vs	LAC	41	20	11	1	0	6	17	35.3	3	6	50.0	5	6	83.3	50.9	0	11	3	2	+11
2	James Harden J. Harden	20	3/6/2023	PHI	@	IND	40	14	9	0	0	3	11	27.3	1	6	16.7	7	9	77.8	46.8	1	8	1	0	+13
3	James Harden J. Harden	17	3/11/2025	LAC	@	NOP	40	25	4	2	0	6	15	40.0	4	11	36.4	9	9	100.0	65.9	0	4	6	3	+5
4	James Harden J. Harden	17	2/8/2025	LAC	vs	UTA	38	23	2	2	0	7	18	38.9	2	8	25.0	7	8	87.5	53.4	0	2	5	1	+30
5	James Harden J. Harden	17	10/31/2022	PHI	@	WAS	38	23	7	2	0	8	17	47.1	2	6	33.3	5	6	83.3	58.6	0	7	4	2	+8
6	James Harden J. Harden	17	3/23/2021	BKN	@	POR	40	25	7	2	0	7	24	29.2	0	7	0.0	11	13	84.6	42.1	0	7	4	2	-5
7	James Harden J. Harden	17	12/26/2020	HOU	@	POR	43	44	4	1	0	12	21	57.1	6	13	46.2	14	16	87.5	78.5	1	3	5	1	-6
8	James Harden J. Harden	17	11/28/2018	HOU	vs	DAL	37	25	11	6	0	7	15	46.7	4	11	36.4	7	9	77.8	65.9	1	10	8	4	-16
9	James Harden J. Harden	17	12/11/2017	HOU	vs	NOP	35	26	1	6	0	8	16	50.0	4	10	40.0	6	9	66.7	65.1	0	1	3	3	-2
10	James Harden J. Harden	17	3/24/2017	HOU	vs	NOP	38	38	7	2	1	12	24	50.0	5	12	41.7	9	11	81.8	65.9	1	6	3	2	+12
11	James Harden J. Harden	17	12/31/2016	HOU	vs	NYK	42	53	16	0	0	14	26	53.8	9	16	56.3	16	18	88.9	78.1	3	13	8	2	+13
12	James Harden J. Harden	17	12/23/2016	HOU	@	MEM	36	16	7	1	0	6	13	46.2	2	6	33.3	2	3	66.7	55.9	1	6	9	5	+10
13	James Harden J. Harden	17	12/10/2016	HOU	vs	DAL	40	18	9	2	0	4	12	33.3	2	8	25.0	8	10	80.0	54.9	0	9	4	1	+21
14	James Harden J. Harden	17	10/26/2016	HOU	@	LAL	37	34	7	1	0	9	19	47.4	1	7	14.3	15	16	93.8	65.3	3	4	7	5	+10
15	James Harden J. Harden	16	11/18/2024	LAC	vs	GSW	41	12	6	2	2	4	15	26.7	2	6	33.3	2	2	100.0	37.8	0	6	3	2	-4
16	James Harden J. Harden	16	10/26/2024	LAC	@	DEN	38	23	6	1	1	5	11	45.5	1	5	20.0	12	13	92.3	68.8	0	6	7	5	+3
17	James Harden J. Harden	16	12/11/2022	PHI	vs	CHA	38	19	9	0	1	6	12	50.0	3	8	37.5	4	5	80.0	66.9	1	8	4	3	+18
18	James Harden J. Harden	16	2/27/2022	PHI	@	NYK	39	29	10	5	0	8	14	57.1	3	7	42.9	10	10	100.0	78.8	0	10	3	4	+19
19	James Harden J. Harden	16	1/12/2022	BKN	@	CHI	33	25	7	1	1	6	13	46.2	5	8	62.5	8	8	100.0	75.7	1	6	2	0	+24
20	James Harden J. Harden	16	2/13/2021	BKN	@	GSW	35	19	8	3	1	6	11	54.5	5	8	62.5	2	2	100.0	80.0	0	8	5	2	+28
21	James Harden J. Harden	16	3/22/2016	HOU	@	OKC	40	24	7	4	0	7	17	41.2	2	8	25.0	8	8	100.0	58.5	0	7	5	6	+1
22	James Harden J. Harden	15	3/4/2025	LAC	@	PHX	38	21	6	2	0	5	14	35.7	2	9	22.2	9	11	81.8	55.7	0	6	1	1	-5
23	James Harden J. Harden	15	1/4/2025	LAC	vs	ATL	29	10	2	2	0	3	9	33.3	1	5	20.0	3	4	75.0	46.5	0	2	4	2	+10
24	James Harden J. Harden	15	4/5/2024	LAC	vs	UTA	33	13	10	0	0	4	10	40.0	2	7	28.6	3	3	100.0	57.4	0	10	5	1	+19
25	James Harden J. Harden	15	12/14/2023	LAC	vs	GSW	42	28	7	1	4	6	12	50.0	5	6	83.3	11	12	91.7	81.0	2	5	4	3	+12