Dwyane Wade averaged 25.4 points, 5.9 assists and 4.9 rebounds in 31 games versus LeBron James in his career.

	NAME	DATE	TM		OPP	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Dwyane Wade D. Wade	11/12/2003	MIA	vs	CLE	35	14	7	5	0	1	5	17	29.4	0	1	0.0	4	5	80.0	36.5	3	4	3	3	+8
2	Dwyane Wade D. Wade	1/28/2004	MIA	@	CLE	24	15	3	5	1	1	6	12	50.0	0	0		3	5	60.0	52.8	1	2	1	0	+12
3	Dwyane Wade D. Wade	4/9/2004	MIA	vs	CLE	41	20	2	7	5	0	5	10	50.0	0	0		10	12	83.3	65.4	2	0	2	2	+17
4	Dwyane Wade D. Wade	4/10/2004	MIA	@	CLE	29	17	4	3	0	0	4	11	36.4	0	0		9	12	75.0	52.2	2	2	2	0	-15
5	Dwyane Wade D. Wade	11/4/2004	MIA	vs	CLE	41	28	6	5	3	3	10	20	50.0	0	0		8	10	80.0	57.4	1	5	2	1	+6
6	Dwyane Wade D. Wade	2/3/2005	MIA	vs	CLE	36	20	5	3	1	1	6	11	54.5	0	0		8	10	80.0	64.9	0	5	4	1	+1
7	Dwyane Wade D. Wade	3/6/2005	MIA	@	CLE	40	18	10	4	2	1	7	22	31.8	0	1	0.0	4	6	66.7	36.5	2	8	6	0	+5
8	Dwyane Wade D. Wade	12/17/2005	MIA	@	CLE	39	33	4	7	2	1	11	22	50.0	0	2	0.0	11	13	84.6	59.5	1	3	2	2	-12
9	Dwyane Wade D. Wade	2/2/2006	MIA	vs	CLE	35	24	4	6	4	1	11	20	55.0	0	0		2	3	66.7	56.3	0	4	3	4	+30
10	Dwyane Wade D. Wade	3/12/2006	MIA	vs	CLE	45	35	9	7	2	1	11	26	42.3	0	0		13	18	72.2	51.6	3	6	2	5	+9
11	Dwyane Wade D. Wade	4/1/2006	MIA	@	CLE	43	44	8	9	2	1	18	36	50.0	1	4	25.0	7	9	77.8	55.1	2	6	1	4	-1
12	Dwyane Wade D. Wade	2/1/2007	MIA	vs	CLE	42	41	4	5	3	2	9	20	45.0	0	1	0.0	23	24	95.8	67.1	0	4	12	0	+12
13	Dwyane Wade D. Wade	2/9/2007	MIA	@	CLE	39	27	1	7	2	2	10	17	58.8	0	0		7	9	77.8	64.4	1	0	7	2	-21
14	Dwyane Wade D. Wade	12/25/2007	MIA	@	CLE	41	22	6	8	0	0	7	18	38.9	0	0		8	16	50.0	43.9	1	5	5	3	-12
15	Dwyane Wade D. Wade	1/21/2008	MIA	vs	CLE	40	42	6	7	3	1	17	29	58.6	1	3	33.3	7	8	87.5	64.6	3	3	4	3	-7
16	Dwyane Wade D. Wade	12/28/2008	MIA	@	CLE	40	29	4	8	2	0	12	25	48.0	0	2	0.0	5	7	71.4	51.6	0	4	2	2	-4
17	Dwyane Wade D. Wade	12/30/2008	MIA	vs	CLE	42	21	5	12	3	1	7	23	30.4	0	3	0.0	7	8	87.5	39.6	2	3	5	1	+9
18	Dwyane Wade D. Wade	3/2/2009	MIA	vs	CLE	40	41	7	9	7	1	16	30	53.3	2	6	33.3	7	9	77.8	60.4	3	4	8	3	-7
19	Dwyane Wade D. Wade	3/7/2009	MIA	@	CLE	41	25	8	12	4	0	9	23	39.1	2	4	50.0	5	5	100.0	49.6	1	7	3	2	+3
20	Dwyane Wade D. Wade	11/12/2009	MIA	vs	CLE	38	36	4	5	0	2	9	21	42.9	3	6	50.0	15	21	71.4	59.5	0	4	4	1	-4
21	Dwyane Wade D. Wade	1/25/2010	MIA	vs	CLE	39	32	10	5	3	1	10	21	47.6	3	5	60.0	9	16	56.3	57.1	3	7	2	1	+2
22	Dwyane Wade D. Wade	2/4/2010	MIA	@	CLE	39	24	3	9	4	0	11	26	42.3	1	3	33.3	1	2	50.0	44.6	3	0	6	4	-16
23	Dwyane Wade D. Wade	12/25/2014	MIA	vs	CLE	37	31	5	5	2	1	12	28	42.9	2	5	40.0	5	5	100.0	51.3	1	4	1	0	+5
24	Dwyane Wade D. Wade	3/16/2015	MIA	vs	CLE	31	32	2	2	5	0	13	18	72.2	0	0		6	8	75.0	74.3	0	2	3	2	+16
25	Dwyane Wade D. Wade	4/2/2015	MIA	@	CLE	13	7	2	0	0	0	2	6	33.3	1	2	50.0	2	4	50.0	45.1	0	2	3	0	-10
	Average					35.6	25.4	4.9	5.9	2.2	0.9	9.1	19.5	46.4	0.7	2.1	31.8	6.6	8.6	76.8	54.5	1.3	3.6	3.7	1.9	2.5
	Total					1,102	788	153	184	69	28	281	606	46.4	21	66	31.8	205	267	76.8	54.5	41	112	116	59	+79