Aditxt (ADTX) has had the highest return this year by a US stock, returning 2,450.8%.

ASSET	YEAR	% RETURN
Aditxt (ADTX)	2025	2,450.76%
Lichen China Limited Class A Ordinary Shares (LICN)	2025	2,318.48%
Fujian Blue Hat Interactive Entertainment Technology (BHAT)	2025	1,916.43%
Diginex Limited Ordinary Shares (DGNX)	2025	1,139.67%
Goldenstone Acquisition Limited Warrants (GDSTW)	2025	548.13%
Mobile-health Network Solutions Class A Ordinary Shares (MNDR)	2025	532.25%
Yoshiharu Global (YOSH)	2025	511.82%
DatChat Inc Series A Warrant (DATSW)	2025	484.78%
Ainos (AIMDW)	2025	407.1%
Dominari (DOMH)	2025	400.16%
Abits (ABTS)	2025	395.3%
error (ZVZZT)	2025	392.31%
Twin Hospitality Group Inc Class A Common Stock When-Issued (TWNPV)	2025	353.13%
Twin Hospitality (TWNP)	2025	346.88%
Aimfinity Investment Corp I Warrant (AIMAW)	2025	328.57%
Mobile Global Esports (MGAM)	2025	325%
Workhorse (WKHS)	2025	263.92%
Wearable Devices (WLDSW)	2025	239.45%
Jiuzi (JZXN)	2025	236.43%
Cohen Circle Acquisition Corp I Warrant (CCIRW)	2025	234.37%
Aclarion (ACONW)	2025	194.5%
Oncology Institute (TOIIW)	2025	178.57%
Neuronetics (STIM)	2025	173.94%
Rapid Micro Biosystems (RPID)	2025	170.33%
CervoMed (CRVO)	2025	168.33%