A2Z Smart Technologies (AZ) had the highest return between 2019 and 2021 by a US stock, returning 4,512,400%.

ASSET	YEARS	% RETURN
A2Z Smart Technologies (AZ)	2019-2021	4,512,400%
Crown Electrokinetics (CRKN)	2019-2021	3,989,900%
XORTX Therapeutics (XRTX)	2019-2021	1,307,380.31%
authID (AUID)	2019-2021	897,820%
Zhihu Inc ADR (ZH)	2019-2021	455,242.47%
Fresh2 (FRES)	2019-2021	433,292.54%
Luokung Technology (LKCO)	2019-2021	348,101.44%
KWESST Micro Systems Inc Common Stock (KWE)	2019-2021	86,695.35%
Kaival Brands Innovations (KAVL)	2019-2021	71,996.77%
Connexa Sports Technologies (YYAI)	2019-2021	68,700%
Oxbridge Re Holdings Equity Warrant (OXBRW)	2019-2021	53,563.64%
Applied Blockchain (APLD)	2019-2021	37,647.75%
Ainos (AIMD)	2019-2021	23,460.21%
Digihost Technology (DGHI)	2019-2021	22,934.83%
NAYA Biosciences (NAYA)	2019-2021	12,707.69%
SDCL EDGE Acquisition (SEDA.UN)	2019-2021	10,363.05%
Draganfly (DPRO)	2019-2021	8,309%
374Water Inc Common Stock (SCWO)	2019-2021	5,600%
Iveda Solutions (IVDA)	2019-2021	5,541.03%
Cassava Sciences (SAVA)	2019-2021	5,041.18%
Wheels Up Experience (UP)	2019-2021	4,708.29%
Accolade (ACCD)	2019-2021	4,692.73%
Sobr Safe (SOBR)	2019-2021	4,355%
Golden Matrix (GMGI)	2019-2021	4,180%
Enphase Energy (ENPH)	2019-2021	3,851.19%