NVIDIA (NVDA) has had the highest return between 2020 and 2025 by a US stock in the S&P 500 (GSPC), returning 1,921.3%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2020-2025	1,921.26%
Super Micro Computer (SMCI)	2020-2025	1,700.84%
Tesla (TSLA)	2020-2025	896.29%
Palantir Technologies Inc Class A Common Stock (PLTR)	2020-2025	747.7%
Crowdstrike (CRWD)	2020-2025	660.02%
Eli Lilly and (LLY)	2020-2025	634.01%
Broadcom (AVGO)	2020-2025	613.51%
Arista Networks (ANET)	2020-2025	612.33%
Axon Enterprise (AXON)	2020-2025	609.86%
Constellation Energy (CEG)	2020-2025	575.89%
Vistra Energy (VST)	2020-2025	541.94%
Quanta Services (PWR)	2020-2025	539.16%
Texas Pacific Land Trust (TPL)	2020-2025	472.54%
Howmet Aerospace (HWM)	2020-2025	470.13%
Carrier Global (CARR)	2020-2025	469.25%
Builders FirstSource (BLDR)	2020-2025	443.77%
Targa Resources (TRGP)	2020-2025	441.32%
Fortinet (FTNT)	2020-2025	397.63%
Deckers Outdoor (DECK)	2020-2025	389.57%
Fair Isaac (FICO)	2020-2025	387.05%
Palo Alto Networks (PANW)	2020-2025	382.34%
KKR (KKR)	2020-2025	375.49%
McKesson (MCK)	2020-2025	362.68%
EQT (EQT)	2020-2025	351.34%
Dell Technologies (DELL)	2020-2025	339.73%