best performing stocks in last 4 years with market cap above 40 billion

NVIDIA (NVDA) has had the highest return between April 5, 2021 and April 5, 2025 by a US stock with a market cap of $40B+, returning 581.6%.

ASSET DATE % RETURN
NVIDIA (NVDA)
4/5/2021 - 4/5/2025
581.58%
Petroleo Brasileiro Petrobras SA ADR (PBR)
4/5/2021 - 4/5/2025
372.42%
Constellation Energy (CEG)
4/5/2021 - 4/5/2025
363.55%
Eli Lilly and (LLY)
4/5/2021 - 4/5/2025
314.97%
MicroStrategy (MSTR)
4/5/2021 - 4/5/2025
313.68%
Petróleo Brasileiro SA - Petrobras (PBR.A)
4/5/2021 - 4/5/2025
299.27%
McKesson (MCK)
4/5/2021 - 4/5/2025
259.22%
Howmet Aerospace  (HWM)
4/5/2021 - 4/5/2025
251.98%
Axon Enterprise (AXON)
4/5/2021 - 4/5/2025
240.03%
Fair Isaac (FICO)
4/5/2021 - 4/5/2025
234.8%
Broadcom (AVGO)
4/5/2021 - 4/5/2025
233.91%
Arista Networks (ANET)
4/5/2021 - 4/5/2025
230.89%
Applovin (APP)
4/5/2021 - 4/5/2025
213.39%
Palantir Technologies Inc Class A Common Stock (PLTR)
4/5/2021 - 4/5/2025
211.23%
Banco Bilbao Viscaya Argentaria SA ADR (BBVA)
4/5/2021 - 4/5/2025
192.23%
Cheniere Energy (LNG)
4/5/2021 - 4/5/2025
183.14%
Energy Transfer (ET)
4/5/2021 - 4/5/2025
183.03%
Progressive (PGR)
4/5/2021 - 4/5/2025
182.63%
Williams Companies (WMB)
4/5/2021 - 4/5/2025
179.15%
Palo Alto Networks (PANW)
4/5/2021 - 4/5/2025
176.7%
O’Reilly Automotive (ORLY)
4/5/2021 - 4/5/2025
171.99%
Costco Wholesale (COST)
4/5/2021 - 4/5/2025
169.3%
MPLX (MPLX)
4/5/2021 - 4/5/2025
168.46%
Arthur J Gallagher (AJG)
4/5/2021 - 4/5/2025
162.27%
AutoZone (AZO)
4/5/2021 - 4/5/2025
156.37%