Super Micro Computer (SMCI) has had the highest return between 2022 and 2025 by a US stock in the S&P 500 (GSPC), returning 730.3%.

ASSET	YEARS	% RETURN
Super Micro Computer (SMCI)	2022-2025	730.31%
Constellation Energy (CEG)	2022-2025	488.31%
Vistra Energy (VST)	2022-2025	483.06%
Palantir Technologies Inc Class A Common Stock (PLTR)	2022-2025	402.61%
Fair Isaac (FICO)	2022-2025	331.66%
Howmet Aerospace (HWM)	2022-2025	323.57%
Targa Resources (TRGP)	2022-2025	315.51%
NVIDIA (NVDA)	2022-2025	282.2%
Axon Enterprise (AXON)	2022-2025	257%
GE Aerospace (GE)	2022-2025	255.1%
Texas Pacific Land Trust (TPL)	2022-2025	246.23%
Eli Lilly and (LLY)	2022-2025	210.93%
Broadcom (AVGO)	2022-2025	188.69%
Royal Caribbean Cruises (RCL)	2022-2025	185.75%
Cardinal Health (CAH)	2022-2025	179.69%
GE Vernova LLC (GEV)	2022-2025	176.47%
Progressive (PGR)	2022-2025	174.68%
McKesson (MCK)	2022-2025	172.6%
Williams Companies (WMB)	2022-2025	168.69%
EQT (EQT)	2022-2025	156.16%
Marathon Petroleum (MPC)	2022-2025	150.54%
NRG Energy (NRG)	2022-2025	150.09%
Transdigm (TDG)	2022-2025	145.63%
Boston Scientific (BSX)	2022-2025	140.29%
T-Mobile US (TMUS)	2022-2025	131.89%