Know Labs (KNW) had the highest return between 2000 and 2007 by a US stock, returning 763,220.6%.

ASSET	YEARS	% RETURN
Know Labs (KNW)	2000-2007	763,220.61%
Perspective Therapeutics (CATX)	2000-2007	669,900%
Gulf Resources (GURE)	2000-2007	55,900%
Frontline (FRO)	2000-2007	26,118.31%
Broadwind Energy (BWEN)	2000-2007	17,060.69%
Denison Mines (DNN)	2000-2007	12,129.59%
Companhia Energetica de Minas Gerais CEMIG Pref ADR (CIG)	2000-2007	11,910.53%
Versus Systems Inc. (VS)	2000-2007	10,020%
Companhia Siderurgica Nacional ADR (SID)	2000-2007	9,864.63%
Dmc Global (BOOM)	2000-2007	9,457.99%
Monster Beverage (MNST)	2000-2007	8,175.34%
Houston American Energy (HUSA)	2000-2007	6,000.38%
RadNet (RDNT)	2000-2007	5,870.59%
Deckers Outdoor (DECK)	2000-2007	5,808.37%
BRF SA ADR (BRFS)	2000-2007	5,334.9%
TherapeuticsMD (TXMD)	2000-2007	4,950.01%
Amedisys (AMED)	2000-2007	4,605.2%
Clean Harbors (CLH)	2000-2007	4,141.88%
Team (TISI)	2000-2007	3,801.87%
Banco Bradesco SA ADR (BBD)	2000-2007	3,667.63%
HF Sinclair (DINO)	2000-2007	3,422.85%
Hudbay Minerals (HBM)	2000-2007	3,170.34%
American Vanguard (AVD)	2000-2007	2,964.38%
Brainstorm Cell Therapeutics (BCLI)	2000-2007	2,935.32%
SSR Mining (SSRM)	2000-2007	2,822.38%