Perspective Therapeutics (CATX) had the highest return between 2000 and 2006 by a US stock, returning 1,633,233.3%.

ASSET	YEARS	% RETURN
Perspective Therapeutics (CATX)	2000-2006	1,633,233.33%
Know Labs (KNW)	2000-2006	194,556.49%
Houston American Energy (HUSA)	2000-2006	14,620.94%
Denison Mines (DNN)	2000-2006	13,873.82%
Gulf Resources (GURE)	2000-2006	13,400%
Frontline (FRO)	2000-2006	10,918.54%
TherapeuticsMD (TXMD)	2000-2006	9,900.01%
Companhia Energetica de Minas Gerais CEMIG Pref ADR (CIG)	2000-2006	8,931.58%
Oramed Pharmaceuticals (ORMP)	2000-2006	6,866.14%
Monster Beverage (MNST)	2000-2006	6,193.05%
Dmc Global (BOOM)	2000-2006	4,441.47%
US Global Investors (GROW)	2000-2006	4,033.8%
Clean Harbors (CLH)	2000-2006	3,871.94%
MEDIFAST (MED)	2000-2006	3,556.96%
HF Sinclair (DINO)	2000-2006	3,431.05%
Versus Systems Inc. (VS)	2000-2006	3,400%
Companhia Siderurgica Nacional ADR (SID)	2000-2006	3,097.71%
Amedisys (AMED)	2000-2006	3,087.55%
AMREP (AXR)	2000-2006	3,057.73%
Hudbay Minerals (HBM)	2000-2006	3,023.71%
BRF SA ADR (BRFS)	2000-2006	2,903.76%
Site Centers (SITC)	2000-2006	2,775.92%
American Vanguard (AVD)	2000-2006	2,697.13%
McEwen Mining (MUX)	2000-2006	2,630.11%
RadNet (RDNT)	2000-2006	2,617.65%