Protalix Biotherapeutics (PLX) had the highest return in December 2005 by a US stock, returning 733.3%.

ASSET	MONTH	% RETURN
Protalix Biotherapeutics (PLX)	December 2005	733.33%
Lisata Therapeutics (LSTA)	December 2005	166.67%
Dominari (DOMH)	December 2005	163.37%
Flux Power (FLUX)	December 2005	138.5%
Marker Therapeutics (MRKR)	December 2005	123.53%
Champions Oncology (CSBR)	December 2005	108.33%
Tanzanian Royalty Exploration (TRX)	December 2005	86.77%
Versus Systems Inc. (VS)	December 2005	80.95%
Under Armour Inc A (UAA)	December 2005	67.69%
Compugen (CGEN)	December 2005	64.48%
Zivo Bioscience (ZIVO)	December 2005	61.54%
Insmed (INSM)	December 2005	53.91%
Data I/O (DAIO)	December 2005	52.73%
EXACT Sciences (EXAS)	December 2005	50.34%
Interlink Electronics (LINK)	December 2005	49.58%
ABVC BioPharma (ABVC)	December 2005	49.5%
Sify Technologies (SIFY)	December 2005	49.03%
Cyclacel Pharmaceuticals (CYCC)	December 2005	48.89%
Simulations Plus (SLP)	December 2005	47.99%
CBAK Energy Technology (CBAT)	December 2005	47.33%
Seabridge Gold (SA)	December 2005	45.06%
Asure Software (ASUR)	December 2005	44.45%
EDAP TMS (EDAP)	December 2005	42.82%
Regeneron Pharmaceuticals (REGN)	December 2005	42.6%
Vera Therapeutics (VERA)	December 2005	40%