Tectonic Therapeutic (TECX) has had the highest return between 2020 and 2024 by a US stock, returning 4,809,900%.

ASSET	YEARS	% RETURN
Tectonic Therapeutic (TECX)	2020-2024	4,809,900%
A2Z Smart Technologies (AZ)	2020-2024	1,156,566.67%
Cadrenal Therapeutics, Inc Common Stock (CVKD)	2020-2024	999,233.33%
Gorilla Technology (GRRR)	2020-2024	477,900%
MGO Global Inc Common Stock (MGOL)	2020-2024	469,900%
Asset Entities Inc Class B Common Stock (ASST)	2020-2024	212,800%
AppTech Payments Corp Warrant (APCXW)	2020-2024	199,700%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2020-2024	131,150%
authID (AUID)	2020-2024	102,400%
Zhihu Inc ADR (ZH)	2020-2024	49,215.07%
Digihost Technology (DGHI)	2020-2024	29,328.57%
Applied Blockchain (APLD)	2020-2024	22,700.93%
Ainos (AIMD)	2020-2024	11,547.5%
XORTX Therapeutics (XRTX)	2020-2024	10,508.7%
Azitra (AZTR)	2020-2024	8,328.57%
Agape ATP Corporation Common Stock (ATPC)	2020-2024	8,220.57%
SDCL EDGE Acquisition (SEDA.UN)	2020-2024	5,505%
Iteris (ITI)	2020-2024	5,412.42%
Digital Brands (DBGIW)	2020-2024	4,754.84%
ZyVersa Therapeutics (ZVSA)	2020-2024	3,921.35%
Kaival Brands Innovations (KAVL)	2020-2024	3,835%
Innodata (INOD)	2020-2024	3,827.19%
Bone Biologics Corp Warrants (BBLGW)	2020-2024	3,243.9%
CPI Card (PMTS)	2020-2024	3,205.56%
Marathon Digital (MARA)	2020-2024	2,857.95%