Xcel Brands (XELB) had the highest return between 2000 and 2004 by a US stock, returning 28,399.9%.

ASSET	YEARS	% RETURN
Xcel Brands (XELB)	2000-2004	28,399.89%
Brainstorm Cell Therapeutics (BCLI)	2000-2004	9,264.8%
Oramed Pharmaceuticals (ORMP)	2000-2004	8,275.95%
Frontline (FRO)	2000-2004	6,120.89%
Axon Enterprise (AXON)	2000-2004	5,326.02%
TherapeuticsMD (TXMD)	2000-2004	4,950.01%
American Vanguard (AVD)	2000-2004	2,306.11%
American Lithium Corp Common Stock (AMLI)	2000-2004	2,300%
Amedisys (AMED)	2000-2004	2,255.75%
Versus Systems Inc. (VS)	2000-2004	2,200%
Meritage (MTH)	2000-2004	1,996.79%
Houston American Energy (HUSA)	2000-2004	1,860.12%
Cheniere Energy (LNG)	2000-2004	1,795.88%
Deckers Outdoor (DECK)	2000-2004	1,690.53%
Flexible Solutions International (FSI)	2000-2004	1,516.06%
NVR (NVR)	2000-2004	1,511.31%
China Yuchai International (CYD)	2000-2004	1,503.46%
Denison Mines (DNN)	2000-2004	1,489.92%
Companhia Siderurgica Nacional ADR (SID)	2000-2004	1,485.28%
Hovnanian Enterprises (HOV)	2000-2004	1,468.95%
Acme United (ACU)	2000-2004	1,385%
Travelzoo (TZOO)	2000-2004	1,368.15%
Inuvo (INUV)	2000-2004	1,363.41%
Site Centers (SITC)	2000-2004	1,317.95%
USANA Health Sciences (USNA)	2000-2004	1,307.64%