Constellation Energy (CEG) has had the highest return between 2022 and 2025 by a US stock in the S&P 500 (GSPC), returning 735.1%.

ASSET	YEARS	% RETURN
Constellation Energy (CEG)	2022-2025	735.06%
Vistra Energy (VST)	2022-2025	727.48%
Super Micro Computer (SMCI)	2022-2025	542.01%
Palantir Technologies Inc Class A Common Stock (PLTR)	2022-2025	342.37%
Fair Isaac (FICO)	2022-2025	326.95%
Targa Resources (TRGP)	2022-2025	320.49%
NVIDIA (NVDA)	2022-2025	318.77%
Axon Enterprise (AXON)	2022-2025	317.26%
Howmet Aerospace (HWM)	2022-2025	301.88%
Deckers Outdoor (DECK)	2022-2025	264.52%
Royal Caribbean Cruises (RCL)	2022-2025	255.9%
GE Aerospace (GE)	2022-2025	251.37%
Broadcom (AVGO)	2022-2025	246.24%
GE Vernova LLC (GEV)	2022-2025	233.24%
Texas Pacific Land Trust (TPL)	2022-2025	229.46%
Arista Networks (ANET)	2022-2025	216.08%
Eli Lilly and (LLY)	2022-2025	209.07%
Quanta Services (PWR)	2022-2025	170.96%
NRG Energy (NRG)	2022-2025	168.53%
Cardinal Health (CAH)	2022-2025	167.76%
Godaddy (GDDY)	2022-2025	152.52%
Williams Companies (WMB)	2022-2025	151.38%
Progressive (PGR)	2022-2025	151.18%
Apollo Global Management LLC Class A (APO)	2022-2025	150.94%
Marathon Petroleum (MPC)	2022-2025	149.35%