NVIDIA (NVDA) had the highest return between 2014 and 2018 by a US stock in the S&P 500 (GSPC), returning 782.1%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2014-2018	782.12%
Caesars Entertainment (CZR)	2014-2018	610%
Paycom Soft (PAYC)	2014-2018	584.08%
Take-Two Interactive Software (TTWO)	2014-2018	496.06%
Texas Pacific Land Trust (TPL)	2014-2018	454.62%
Broadcom (AVGO)	2014-2018	428.58%
Netflix (NFLX)	2014-2018	410.79%
Advanced Micro Devices (AMD)	2014-2018	379.48%
Edwards Lifesciences (EW)	2014-2018	366.41%
Centene (CNC)	2014-2018	291.11%
Adobe Systems (ADBE)	2014-2018	283.07%
Arista Networks (ANET)	2014-2018	281.36%
Amazon (AMZN)	2014-2018	276.62%
Domino's Pizza Inc Common Stock (DPZ)	2014-2018	275.52%
Intuitive Surgical (ISRG)	2014-2018	274.51%
Fortinet (FTNT)	2014-2018	267.59%
Align Technology (ALGN)	2014-2018	267.03%
CDW (CDW)	2014-2018	263.98%
UnitedHealth (UNH)	2014-2018	259.58%
MSCI (MSCI)	2014-2018	256.78%
Monolithic Power Systems (MPWR)	2014-2018	255.67%
IDEXX Laboratories (IDXX)	2014-2018	251.05%
Electronic Arts (EA)	2014-2018	244.59%
DexCom (DXCM)	2014-2018	239.86%
EPAM Systems (EPAM)	2014-2018	233.55%